Warfarin Tablets

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Therapeutic Indication

Prevention and treatment of venous thrombosis
Prevention of pulmonary embolism
Stroke prevention in atrial fibrillation
Prevention of thromboembolic events in prosthetic heart valves
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Warfarin

Tablet

Warfarin is a vitamin K antagonist anticoagulant used to prevent and treat blood clots. It works by inhibiting vitamin K-dependent clotting factors, thereby reducing the risk of thrombosis and embolism.

Speciality Cardiology | Hematology | Internal Medicine
Tags Anticoagulant | Blood Clot Prevention | Stroke Risk Reduction | Vitamin K Antagonist
Strength
  • 2 mg
  • 5 mg
Packing Size
  • 10 Tablets

Check all Tablets Range

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Mechanism

Warfarin inhibits vitamin K epoxide reductase, preventing activation of clotting factors II, VII, IX, and X. This reduces thrombin formation and clot development.

Pharmacokinetics

  • Absorption: Well absorbed orally
  • Distribution: Highly protein-bound
  • Metabolism: Hepatic metabolism via CYP450
  • Excretion: Renal and biliary
  • Half-life: 20–60 hours

Side Effects

  • Bleeding (major and minor)
  • Bruising
  • Rare: Skin necrosis, purple toe syndrome

Contraindication

  • Pregnancy (teratogenic)
  • Active bleeding
  • Conditions with high risk of bleeding
  • Recent surgery with high bleeding risk

Interaction

  • Antibiotics: May increase INR and bleeding risk.
  • NSAIDs, Aspirin: Increase bleeding risk.
  • Vitamin K-rich foods: Reduce effectiveness.
  • CYP450 inducers/inhibitors: Alter warfarin metabolism.

Warning and Precautions

  • Regular INR monitoring is essential.
  • Maintain consistent dietary vitamin K intake.
  • Report signs of bleeding immediately.
  • Adjust dose carefully under physician supervision.

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.