Thiocolchicoside + Ketoprofen Tablets

Project Image
Thumb Image

Therapeutic Indication

Musculoskeletal pain
Inflammation
Muscle spasms
Arthritis-related pain
+91 85919 78885

Thiocolchicoside + Ketoprofen

Tablet

Ketoprofen + Thiocolchicoside is a combination of two medicines: Ketoprofen and Thiocolchicoside which relieve pain and relax the muscles. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

Speciality Orthopedics | Rheumatology | Internal Medicine
Tags Muscle Relaxant | NSAID | Pain Relief | Anti-inflammatory
Strength
  • Thiocolchicoside 4 mg + Ketoprofen 50 mg
Packing Size
  • 10 Tablets

Check all Tablets Range

Click to know More

Mechanism

Thiocolchicoside acts on GABA receptors to relax muscles and reduce spasms. Ketoprofen inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis and thereby alleviating pain and inflammation.

Pharmacokinetics

  • Absorption: Both drugs are well absorbed orally.
  • Metabolism: Thiocolchicoside metabolized hepatically; Ketoprofen metabolized in liver.
  • Excretion: Primarily via urine.
  • Half-life: Thiocolchicoside ~7 hours; Ketoprofen ~2–4 hours.

Side Effects

  • Gastrointestinal discomfort
  • Nausea
  • Drowsiness
  • Dizziness
  • Rare: Allergic reactions, hepatotoxicity

Contraindication

  • Hypersensitivity to thiocolchicoside or ketoprofen
  • Peptic ulcer disease
  • Severe hepatic or renal impairment
  • Pregnancy and lactation

Interaction

  • Other NSAIDs (increased GI risk)
  • Anticoagulants (enhanced bleeding risk)
  • CNS depressants (additive sedation)

Warning and Precautions

  • Use cautiously in patients with GI disorders
  • Monitor liver and kidney function during therapy
  • Not recommended during pregnancy unless essential

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.