Serratiopeptidase Tablets

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Therapeutic Indication

Pain relief
Fever reduction
Inflammatory conditions
Musculoskeletal pain
Dysmenorrhea
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Nimesulide + Serratiopeptidase

Tablet

Serratiopeptidase is a proteolytic enzyme used to reduce inflammation, swelling, and pain. It is prescribed for post-surgical recovery, traumatic injuries, arthritis, and respiratory conditions with excessive mucus.

Speciality Anti-inflammatory | Enzyme Therapy | Pain Relief | Post-surgical Recovery
Tags Enzyme Therapy | Anti-inflammatory | Pain Relief | Swelling Reduction | Post-surgical Care
Strength
  • 10 mg
Packing Size
  • 10 Tablets

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Mechanism

Serratiopeptidase is a proteolytic enzyme that breaks down inflammatory mediators and fibrin deposits, reducing swelling and promoting faster tissue healing. It also helps in thinning mucus secretions in respiratory conditions.

Pharmacokinetics

  • Absorption: Nimesulide is rapidly absorbed orally with peak plasma levels in 1.5–3 hrs; Serratiopeptidase is absorbed from the intestine and reaches systemic circulation bound to alpha-2 macroglobulin.
  • Distribution: Nimesulide is ~99% plasma protein bound; Serratiopeptidase distributes to inflamed tissues.
  • Metabolism: Nimesulide undergoes hepatic metabolism via CYP enzymes; Serratiopeptidase is metabolized as a protein enzyme.
  • Excretion: Nimesulide is primarily excreted via urine and bile; Serratiopeptidase is eliminated through renal pathways.
  • Half-life: Nimesulide ~2–5 hrs; Serratiopeptidase ~1 hr (enzyme activity dependent).

Side Effects

  • Gastrointestinal upset
  • Nausea
  • Skin rash (rare)
  • Allergic reactions (rare)

Contraindication

  • Hypersensitivity to Serratiopeptidase
  • Bleeding disorders
  • Pregnancy & lactation (use cautiously)

Interaction

  • May increase bleeding risk with anticoagulants
  • Use cautiously with other anti-inflammatory drugs

Warning and Precautions

  • Do not exceed recommended daily dose
  • Monitor patients with bleeding tendencies
  • Discontinue if allergic reaction occurs

Dosage

As directed by the Physician.

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As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.