Saxagliptin Tablets

Project Image
Thumb Image

Therapeutic Indication

Type 2 Diabetes Mellitus
Improves glycemic control
Adjunct to diet and exercise
+91 85919 78885

Saxagliptin

Tablet

Saxagliptin is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor that increases incretin levels, enhancing insulin secretion and reducing glucagon release. It is prescribed for the management of type 2 diabetes mellitus.

Speciality Endocrinology | Internal Medicine
Tags DPP-4 Inhibitor | Antidiabetic
Strength
  • 2.5 mg
  • 5 mg
Packing Size
  • 10 Tablets

Check all Tablets Range

Click to know More

Mechanism

Saxagliptin inhibits DPP-4 enzyme, prolonging incretin activity, which increases insulin release and decreases glucagon secretion in a glucose-dependent manner.

Pharmacokinetics

  • Absorption: Rapid after oral administration
  • Metabolism: Hepatic via CYP3A4/5
  • Elimination: Renal excretion
  • Half-life: Approximately 2.5 hours (active metabolite ~3 hours)

Side Effects

  • Nasopharyngitis
  • Headache
  • Urinary tract infection
  • Rare: Pancreatitis

Contraindication

  • Hypersensitivity to Saxagliptin
  • Severe renal impairment without dose adjustment

Interaction

  • Other antidiabetic agents (risk of hypoglycemia)
  • Strong CYP3A4/5 inhibitors may increase Saxagliptin levels

Warning and Precautions

  • Monitor renal function regularly
  • Discontinue if pancreatitis is suspected
  • Use with caution in hepatic impairment

Dosage

As directed by the Physician.