Racecadotril Tablets

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Therapeutic Indication

Acute diarrhea in adults
Adjunct therapy in pediatric diarrhea
Helps reduce intestinal fluid secretion
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Racecadotril

Tablet

Cisapride is a prokinetic agent used to enhance gastrointestinal motility. It increases acetylcholine release in the enteric nervous system, improving esophageal clearance and gastric emptying. Due to cardiac risks, its use is restricted and requires strict medical supervision.

Speciality Gastroenterology
Tags Diarrhea | Antisecretory | Gastroenterology | Pediatric Use
Strength
  • 30 mg
Packing Size
  • 10 Tablets

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Mechanism

Racecadotril is a prodrug converted to thiorphan, which inhibits enkephalinase. This prevents degradation of endogenous enkephalins, reducing intestinal hypersecretion of water and electrolytes without altering gut motility.

Pharmacokinetics

  • Absorption: Rapidly absorbed orally.
  • Distribution: Widely distributed in tissues.
  • Metabolism: Converted to active metabolite thiorphan.
  • Elimination: Excreted via urine and feces.
  • Half-life: ~3 hours.

Side Effects

  • Nausea
  • Headache
  • Skin rash
  • Abdominal pain
  • Rare allergic reactions

Contraindication

  • Chronic diarrhea
  • Hypersensitivity to Racecadotril
  • Severe renal or hepatic impairment
  • Infants under 3 months

Interaction

  • No major drug interactions reported
  • Safe with oral rehydration therapy
  • Use cautiously with other antidiarrheal agents

Warning and Precautions

  • Use under medical supervision
  • Not a substitute for rehydration therapy
  • Monitor hydration status in children
  • Discontinue if allergic reaction occurs

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.