Olanzapine Tablets

Project Image
Thumb Image
Thumb Image
Thumb Image
Thumb Image

Therapeutic Indication

Schizophrenia
Bipolar disorder (manic or mixed episodes)
Maintenance therapy in bipolar disorder
Adjunct in treatment-resistant depression
+91 85919 78885

Olanzapine

Tablet

Olanzapine is an atypical antipsychotic used to manage schizophrenia and bipolar disorder. It works by modulating dopamine and serotonin receptors in the brain.

Speciality Psychiatry | Neurology
Tags Schizophrenia | Bipolar Disorder | Depression
Strength
  • 5 mg
  • 10 mg
  • 15 mg
Packing Size
  • 10 Tablets
  • 15 Tablets

Check all Tablet Range

Click to know More

Mechanism

Olanzapine antagonizes dopamine D2 and serotonin 5-HT2A receptors, reducing psychotic symptoms and stabilizing mood.

Pharmacokinetics

  • Absorption: Well absorbed orally.
  • Metabolism: Extensively metabolized in liver (CYP1A2).
  • Excretion: Via urine and feces.
  • Half-life: ~30 hours.

Side Effects

  • Weight gain
  • Somnolence
  • Increased appetite
  • Hyperglycemia
  • Dyslipidemia

Contraindication

  • Hypersensitivity to Olanzapine
  • History of drug-induced agranulocytosis

Interaction

  • CYP1A2 inhibitors (fluvoxamine)
  • CYP1A2 inducers (smoking, carbamazepine)
  • Alcohol (enhanced sedation)

Warning and Precautions

  • Monitor weight, glucose, and lipid profile
  • Use with caution in elderly patients with dementia-related psychosis
  • Risk of metabolic syndrome