Norfloxacin Tablets

Megestrol Tablet

Therapeutic Indication

Urinary tract infections (UTIs)
Gastrointestinal infections
Prostatitis
Selected respiratory tract infections
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Norfloxacin

Tablet

Norfloxacin is a fluoroquinolone antibiotic used to treat bacterial infections, particularly of the urinary tract and gastrointestinal system. It works by inhibiting bacterial DNA gyrase, preventing replication and growth.

Speciality Internal Medicine / Infectious Diseases
Tags Antibiotic | Fluoroquinolone
Strength
  • 400 mg
Packing Size
  • 10 Tablets

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Mechanism

Norfloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair, leading to bacterial cell death.

Pharmacokinetics

  • Absorption: Rapid oral absorption
  • Metabolism: Limited hepatic metabolism
  • Elimination: Primarily renal excretion
  • Half-life: 3–4 hours

Side Effects

  • Nausea
  • Diarrhea
  • Dizziness
  • Photosensitivity

Contraindication

  • Hypersensitivity to fluoroquinolones
  • Pregnancy and breastfeeding
  • Children and adolescents (risk of cartilage damage)

Interaction

  • Antacids (reduce absorption)
  • Warfarin (may increase INR)
  • Other QT-prolonging drugs

Warning and Precautions

  • Avoid excessive sunlight exposure
  • Use with caution in renal impairment
  • Discontinue if tendon pain or inflammation occurs

Dosage

As directed by the Physician.