Melatonin Tablets

Therapeutic Indication

Insomnia

Jet lag management

Delayed sleep phase disorder

Adjunct in circadian rhythm disturbances

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Melatonin

Tablet

Melatonin is a naturally occurring hormone that regulates the sleep-wake cycle. Supplementation helps improve sleep quality, reduce insomnia, and manage jet lag by synchronizing circadian rhythms.

Speciality	Neurology \| Psychiatry \| General Medicine
Tags	Sleep Aid \| Insomnia \| Circadian Rhythm
Strength	3 mg
Packing Size	10 Tablets

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Mechanism

Melatonin binds to MT1 and MT2 receptors in the brain, regulating circadian rhythms and promoting sleep onset. It reduces sleep latency and improves overall sleep quality.

Pharmacokinetics

Absorption: Rapidly absorbed after oral administration; peak plasma concentration in 30–60 minutes.
Distribution: Widely distributed; crosses blood-brain barrier.
Metabolism: Extensively metabolized in the liver via CYP1A2.
Elimination: Excreted via urine as metabolites.
Half-life: Approximately 30–60 minutes.

Side Effects

Drowsiness
Headache
Dizziness
Rare: vivid dreams, mood changes

Contraindication

CYP1A2 inhibitors (increase melatonin levels)
Alcohol (reduces effectiveness)
Sedatives (additive effect)

Interaction

CYP1A2 inhibitors (increase melatonin levels)
Alcohol (reduces effectiveness)
Sedatives (additive effect)

Warning and Precautions

May cause drowsiness; avoid driving after use
Use cautiously in patients with depression
Consult physician before long-term use

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.