Mefenamic Acid

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Therapeutic Indication

Pain relief (mild to moderate)
Dysmenorrhea (menstrual pain)
Musculoskeletal pain
Dental pain
Headache
Post-operative pain
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Mefenamic Acid

Tablet

Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) widely used for pain management. It provides analgesic, anti-inflammatory, and antipyretic effects, making it effective in dysmenorrhea, musculoskeletal pain, dental pain, and headache.

Speciality General Medicine | Gynecology | Orthopedics | Dentistry
Tags Analgesic | Antipyretic | NSAID
Strength
  • 100 mg
Packing Size
  • 10 Tablets

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Mechanism

Mefenamic Acid inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis. This decreases inflammation, pain, and fever, providing symptomatic relief in various conditions.

Pharmacokinetics

  • Absorption: Rapidly absorbed orally.
  • Distribution: Highly protein bound (~90%).
  • Metabolism: Extensively metabolized in the liver.
  • Elimination: Excreted in urine as metabolites.
  • Half-life: ~2 hours.

Side Effects

  • Gastrointestinal discomfort
  • Nausea
  • Dizziness
  • Headache
  • Rare: Gastric ulceration

Contraindication

  • Hypersensitivity to Mefenamic Acid
  • Peptic ulcer disease
  • Severe hepatic impairment
  • Pregnancy (use with caution)

Interaction

  • Other NSAIDs (additive GI risk)
  • Warfarin (may increase bleeding risk)
  • Alcohol (increases gastric irritation)

Warning and Precautions

  • Use under medical supervision only
  • Caution in patients with gastric ulcer history
  • Monitor liver function in long-term use

Dosage

As directed by the Physician.