Lornoxicam +
paracetamol Tablets

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Therapeutic Indication

Acute pain management
Osteoarthritis
Rheumatoid arthritis
Post-operative pain
Musculoskeletal pain
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Lornoxicam + Paracetamol

Tablet

Lornoxicam and Paracetamol is a powerful combination used for effective relief from pain and inflammation. It combines the anti-inflammatory action of Lornoxicam with the analgesic and antipyretic effect of Paracetamol. This combination provides rapid onset of action and is widely used in conditions like arthritis, post-operative pain, musculoskeletal disorders, and acute painful conditions. It is especially beneficial in providing faster and stronger pain relief compared to single-drug therapy and should be used under medical supervision.

Speciality NSAID | Analgesic Combination
Tags Pain Relief | Anti-inflammatory | Fever Control
Strength
  • Lornoxicam 4 mg/ 8 mg
  • Paracetamol 325 mg
Packing Size
  • 10 Tablets

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Mechanism

Lornoxicam inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis responsible for pain and inflammation. Paracetamol acts centrally by inhibiting prostaglandin synthesis in the brain, providing analgesic and antipyretic effects. Together, they provide enhanced and rapid pain relief.

Pharmacokinetics

  • Absorption: Rapid oral absorption with quick onset of action.
  • Distribution: Widely distributed in body tissues.
  • Metabolism: Metabolized in liver.
  • Elimination: Excreted via urine.

Side Effects

  • Nausea and vomiting
  • Stomach pain or indigestion
  • Diarrhea
  • Dizziness
  • Rarely gastrointestinal irritation

Contraindication

  • Peptic ulcer or gastrointestinal bleeding
  • Severe liver or kidney disease
  • Hypersensitivity to NSAIDs or Paracetamol
  • Pregnancy and lactation

Interaction

  • Anticoagulants (increased bleeding risk)
  • Methotrexate (increased toxicity)
  • ACE inhibitors and diuretics
  • Alcohol (increased liver toxicity risk)

Warning and Precautions

  • Use lowest effective dose
  • Monitor liver and kidney function
  • Avoid long-term unsupervised use
  • Use cautiously in elderly patients