Levofloxacin + Ornidazole Tablets

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Therapeutic Indication

Bacterial infections (respiratory, urinary, gastrointestinal)
Protozoal infections (amoebiasis, giardiasis)
Mixed infections causing diarrhea and dysentery
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Levofloxacin + Ornidazole

Tablet

Combination medicine used to treat bacterial and protozoal infections. Levofloxacin is a fluoroquinolone antibiotic, while Ornidazole is an antiprotozoal and antibacterial agent.

Speciality Infectious Diseases | Gastroenterology | Internal Medicine
Tags Antibiotic | Antiprotozoal | Diarrhea Treatment
Strength
  • Levofloxacin 250 mg
  • Ornidazole 500 mg
Packing Size
  • 10 Tablets

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Mechanism

Levofloxacin inhibits bacterial DNA gyrase, preventing replication. Ornidazole disrupts DNA synthesis in protozoa and anaerobic bacteria, leading to cell death.

Pharmacokinetics

  • Absorption: Rapid oral absorption.
  • Distribution: Wide tissue penetration.
  • Metabolism: Hepatic metabolism (Ornidazole); minimal metabolism for Levofloxacin.
  • Elimination: Renal excretion.
  • Half-life: Levofloxacin ~6–8 hrs; Ornidazole ~12–14 hrs.

Side Effects

  • Nausea, vomiting, diarrhea
  • Dizziness, headache
  • Metallic taste
  • Rare: tendon rupture (Levofloxacin), seizures (Ornidazole)

Contraindication

  • Hypersensitivity to fluoroquinolones or nitroimidazoles
  • Severe liver disease
  • Pregnancy and breastfeeding (unless prescribed)

Interaction

  • Antacids (reduce levofloxacin absorption)
  • Warfarin (increased bleeding risk)
  • Alcohol (increases Ornidazole side effects)

Warning and Precautions

  • Use under medical supervision only
  • Monitor liver function during prolonged use
  • Avoid driving if dizziness occurs

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.