Glucosamine +
Chondroitin Tablets

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Therapeutic Indication

Osteoarthritis management
Joint pain and stiffness relief
Improved mobility and flexibility
Support for cartilage repair and maintenance
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Glucosamine + Chondroitin

Tablet

Glucosamine and chondroitin are marketed to people with osteoarthritis and to athletes who experience overuse injuries as a way to relieve pain and increase range of motion. They are sometimes referred to as slow acting osteoarthritis drugs. Glucosamine is made from glucose and glutamine. It is incorporated into glycosaminoglycans (unbranched polysaccharides) which are incorporated into proteoglycans (proteins that contain glycosaminoglycans). Proteoglycans are found in every tissue in the body, primarily in the extracellular matrix, and are remarkable for their ability to attract water. Chondroitin is one of at least seven glycosaminoglycans and is a primary component of cartilage. Because of its ability to attract water, chondroitin sulfate helps to lubricate the joints.

Speciality Joint Health Supplement
Tags Joint Health | Osteoarthritis | Mobility Support
Strength
  • Glucosamine 500 mg
  • Chondroitin 400 mg
Packing Size
  • 10 Tablets

Check all Tablet Range

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Mechanism

The mechanism of action of glucosamine or chondroitin is unknown but it is hypothesized that each may inhibit lysosomal enzymes or may stimulate proteoglycan synthesis. The mechanism is different from NSAIDs, which inhibit cyclooxygenase.

Pharmacokinetics

  • Absorption: Well absorbed orally
  • Distribution: Concentrated in joint tissues
  • Metabolism: Minimal hepatic metabolism
  • Elimination: Primarily renal excretion
  • Half-life: 2–3 hours

Side Effects

  • Nausea
  • Diarrhea
  • Constipation
  • Abdominal discomfort

Contraindication

  • Hypersensitivity to glucosamine, chondroitin, or shellfish
  • Severe renal impairment

Interaction

  • Warfarin (may increase bleeding risk)
  • Other anticoagulants (monitor closely)

Warning and Precautions

  • Monitor blood sugar in diabetic patients
  • Use cautiously in patients with shellfish allergy
  • Consult healthcare provider for long-term use