Gatifloxacin Tablets

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Therapeutic Indication

Bacterial infections (respiratory, urinary, gastrointestinal)
Skin and soft tissue infections
Eye infections (ophthalmic use)
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Gatifloxacin

Tablet

Gatifloxacin is a fluoroquinolone antibiotic used to treat a variety of bacterial infections. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair, thereby preventing bacterial growth.

Speciality Infectious Diseases
Tags Antibiotic | Respiratory Infections | UTI | Ophthalmic
Strength
  • 200 mg
  • 400 mg
Packing Size
  • 10 Tablets

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Mechanism

Gatifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair. This leads to rapid bacterial cell death and effective control of infection.

Pharmacokinetics

  • Absorption: Rapidly absorbed orally, bioavailability ~96%.
  • Distribution: Widely distributed in tissues and fluids.
  • Metabolism: Minimal hepatic metabolism.
  • Elimination: Primarily renal excretion.
  • Half-life: ~7–14 hours.

Side Effects

  • Nausea, diarrhea
  • Dizziness, headache
  • Photosensitivity
  • Risk of dysglycemia (blood sugar changes)
  • QT prolongation (cardiac risk)

Contraindication

  • History of hypersensitivity to fluoroquinolones
  • Diabetic patients (risk of dysglycemia)
  • Cardiac arrhythmias
  • Pregnancy and lactation (use with caution)

Interaction

  • Antidiabetic drugs (risk of hypoglycemia/hyperglycemia)
  • Antiarrhythmic drugs (QT prolongation)
  • NSAIDs (risk of seizures)
  • Iron, zinc, and antacids (reduce absorption)

Warning and Precautions

  • Use under medical supervision
  • Monitor blood sugar levels in diabetic patients
  • Avoid excessive sun exposure
  • Monitor ECG in patients with cardiac risk
  • Not recommended in children

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.