Flavoxate +
Ofloxacin Tablets

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Therapeutic Indication

Urinary tract infections (UTI)
Burning micturition (dysuria)
Urinary urgency & frequency
Bladder spasm & irritation
Post-instrumentation urinary discomfort
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Flavoxate + Ofloxacin

Tablet

Flavoxate + Ofloxacin is a synergistic combination designed for effective management of urinary tract infections along with relief from associated bladder spasms and discomfort. Ofloxacin eliminates the infection-causing bacteria, while Flavoxate relaxes urinary tract muscles, providing rapid symptomatic relief from pain, urgency, and frequency. This dual-action therapy ensures faster recovery and improved patient comfort.

Speciality Antibiotic | Urinary Antispasmodic
Tags UTI Care | Infection Control | Bladder Relief
Strength
  • Flavoxate 200 mg
  • Ofloxacin 200 mg
Packing Size
  • 10 Tablets

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Mechanism

This combination works through a dual mechanism targeting both the cause and symptoms of urinary tract infections.
Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV enzymes, preventing DNA replication and leading to bacterial cell death.
Flavoxate acts directly on urinary tract smooth muscles by inhibiting phosphodiesterase activity and reducing calcium influx, resulting in muscle relaxation and relief from bladder spasms.
Together, the combination ensures eradication of infection along with rapid relief from pain, urgency, burning sensation, and discomfort, improving overall treatment outcomes.

Pharmacokinetics

  • Absorption: Well absorbed orally
  • Distribution: Good tissue penetration, especially urinary tract
  • Metabolism: Partial hepatic metabolism
  • Elimination: Mainly via urine

Side Effects

  • Nausea
  • Dizziness
  • Dry mouth
  • Abdominal discomfort

Contraindication

  • Hypersensitivity to fluoroquinolones
  • History of tendon disorders
  • Severe renal impairment (dose adjustment required)
  • Pregnancy & lactation

Interaction

  • Antacids (reduce absorption of Ofloxacin)
  • NSAIDs (increase CNS stimulation risk)
  • Anticholinergic drugs

Warning and Precautions

  • Avoid in children unless prescribed
  • Stay hydrated during treatment
  • Use cautiously in elderly patients
  • Complete full antibiotic course