Ethambutol Tablets

Therapeutic Indication

Tuberculosis (always in combination therapy)

Drug-resistant TB regimens

Ethambutol

Tablet

Ethambutol is an antituberculosis agent used in combination therapy to prevent resistance and improve treatment outcomes. It must be taken under strict medical supervision due to risks of optic neuritis and vision loss.

Speciality	Infectious Diseases \| Pulmonology \| Internal Medicine
Tags	Antituberculosis \| TB Treatment \| Myambutol
Strength	400 mg
Packing Size	10 Tablets

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Mechanism

Ethambutol inhibits arabinosyl transferases involved in cell wall synthesis of Mycobacterium tuberculosis, weakening the bacterial cell wall and preventing growth.

Pharmacokinetics

Absorption: Well absorbed orally.
Distribution: Widely distributed; reaches lungs and kidneys.
Metabolism: Minimal hepatic metabolism.
Elimination: Primarily renal excretion.
Half-life: ~3–4 hours.

Side Effects

Nausea, vomiting
Headache, dizziness
Joint pain
Vision changes (blurred vision, color blindness)
Rare: optic neuritis, liver dysfunction

Contraindication

Optic neuritis
Severe kidney disease
Hypersensitivity to ethambutol

Interaction

Other TB drugs (monitor liver function)
Antacids (reduce absorption)

Warning and Precautions

Regular eye exams required
Monitor liver and kidney function
Never use as monotherapy

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.