Enalapril Tablets

Megestrol Tablet

Therapeutic Indication

Hypertension (high blood pressure)
Congestive heart failure
Prevention of symptomatic heart disease progression
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Enalapril

Tablet

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor used to treat hypertension and heart failure. It reduces blood pressure and cardiac workload by inhibiting the conversion of angiotensin I to angiotensin II.

Speciality Cardiology | Internal Medicine | Nephrology
Tags ACE Inhibitor | Hypertension | Heart Failure | Blood Pressure Control
Strength
  • 2.5 mg
  • 5 mg
  • 10 mg
Packing Size
  • 10 Tablets

Check all Tablets Range

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Mechanism

Enalapril inhibits angiotensin-converting enzyme (ACE), preventing the formation of angiotensin II, a potent vasoconstrictor. This leads to vasodilation, reduced blood pressure, and decreased cardiac workload.

Pharmacokinetics

  • Absorption: Well absorbed orally; bioavailability ~60%.
  • Metabolism: Prodrug converted to active metabolite enalaprilat in liver.
  • Excretion: Primarily via urine.
  • Half-life: Enalaprilat ~11 hours.

Side Effects

  • Cough (common with ACE inhibitors)
  • Dizziness
  • Hyperkalemia
  • Hypotension
  • Rare: Angioedema

Contraindication

  • History of angioedema with ACE inhibitors
  • Pregnancy
  • Severe renal impairment
  • Bilateral renal artery stenosis

Interaction

  • Potassium-sparing diuretics (risk of hyperkalemia)
  • NSAIDs (may reduce antihypertensive effect)
  • Other antihypertensives (additive effect)
  • Lithium (risk of toxicity)

Warning and Precautions

  • Monitor renal function and electrolytes regularly
  • Use cautiously in elderly patients
  • Discontinue if angioedema occurs
  • Not recommended during pregnancy

Dosage

As directed by the Physician.