Doxycycline Tablets

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Therapeutic Indication

Bacterial infections (respiratory, urinary, skin, eye)
Sexually transmitted infections (chlamydia, syphilis, gonorrhea)
Acne vulgaris
Malaria prophylaxis
Periodontitis
Rickettsial infections (Rocky Mountain spotted fever, typhus)
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Prednisolone

Tablet

Doxycycline is a broad-spectrum tetracycline-class antibiotic. It is widely used for bacterial infections, malaria prophylaxis, and acne management. Its favorable pharmacokinetics and broad coverage make it a versatile antimicrobial agent.

Speciality Infectious Diseases | Dermatology | Travel Medicine
Tags Antibiotic | Tetracycline | Malaria Prophylaxis | Acne Treatment
Strength
  • 100 mg
Packing Size
  • 10 Tablets

Mechanism

Doxycycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. This prevents aminoacyl-tRNA attachment, halting bacterial growth and replication.

Pharmacokinetics

  • Absorption: Rapid oral absorption; bioavailability ~90–100%.
  • Distribution: Widely distributed; crosses placenta.
  • Metabolism: Limited hepatic metabolism.
  • Elimination: Excreted in urine and feces.
  • Half-life: ~18–22 hours.

Side Effects

  • Nausea, vomiting, diarrhea
  • Photosensitivity (sunburn risk)
  • Esophageal irritation
  • Tooth discoloration (children)
  • Rare: hepatotoxicity

Contraindication

  • Hypersensitivity to tetracyclines
  • Pregnancy and breastfeeding
  • Children under 8 years (tooth discoloration risk)

Interaction

  • Antacids and iron supplements: Reduce absorption.
  • Warfarin: Increased anticoagulant effect.
  • Oral contraceptives: Reduced efficacy.

Warning and Precautions

  • Take with plenty of water to avoid esophageal irritation.
  • Avoid excessive sun exposure due to photosensitivity risk.
  • Adjust dose in patients with hepatic impairment.

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.