Dimenhydrinate Tablets

Therapeutic Indication

Motion sickness (nausea, vomiting, dizziness)

Vertigo management

Adjunct in nausea and vomiting of other causes

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Dimenhydrinate

Tablet

Dimenhydrinate is an antihistamine with antiemetic properties, commonly used to prevent and treat motion sickness. It reduces nausea, vomiting, and dizziness by blocking histamine and muscarinic receptors in the brain.

Speciality	ENT \| Neurology \| General Medicine
Tags	Antiemetic \| Antihistamine \| Motion Sickness
Strength	50 mg
Packing Size	10 Tablets

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Mechanism

Dimenhydrinate works by blocking histamine H1 receptors and muscarinic receptors in the vomiting center and vestibular system. This reduces stimulation that causes nausea, vomiting, and dizziness.

Pharmacokinetics

Absorption: Rapidly absorbed after oral administration; onset within 15–30 minutes.
Distribution: Widely distributed; crosses blood-brain barrier.
Metabolism: Extensively metabolized in the liver.
Elimination: Excreted via urine.
Half-life: Approximately 3–6 hours.

Side Effects

Drowsiness
Dry mouth
Blurred vision
Constipation
Rare: confusion, urinary retention

Contraindication

Hypersensitivity to dimenhydrinate or diphenhydramine
Severe asthma
Glaucoma
Prostatic hypertrophy

Interaction

Alcohol (enhances sedation)
CNS depressants (additive effect)
Anticholinergic drugs (increased side effects)

Warning and Precautions

May cause drowsiness; avoid driving or operating machinery
Use cautiously in elderly patients
Not recommended in children under 2 years

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.