Diclofenac + Serratiopeptidase Tablets

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Therapeutic Indication

Musculoskeletal pain and inflammation
Post-surgical swelling and pain
Arthritis and joint stiffness
Soft tissue injuries and trauma
Dental pain and swelling
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Diclofenac + Serratiopeptidase

Tablet

This combination provides dual action therapy: Diclofenac reduces pain and inflammation, while Serratiopeptidase enzymatically reduces swelling and promotes faster healing.

Speciality Orthopedics | Dentistry | General Medicine
Tags Pain Relief | Anti-inflammatory | Enzyme Therapy
Strength
  • Diclofenac Potassium 50 mg
  • Serratiopeptidase 10 mg
Packing Size
  • 10 Tablets

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Mechanism

  • Diclofenac: Inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis → anti-inflammatory and analgesic effect.
  • Serratiopeptidase: Breaks down inflammatory mediators and fibrin deposits → reduces edema and accelerates healing.

Pharmacokinetics

  • Diclofenac: Rapid absorption, >99% plasma protein binding, half-life 1–2 hrs.
  • Serratiopeptidase: Absorbed via intestinal mucosa, functional activity ~6–8 hrs.

Side Effects

  • GI upset, nausea, headache
  • Dizziness
  • Rare allergic reactions

Contraindication

  • Hypersensitivity to Diclofenac or Serratiopeptidase
  • Pregnancy & lactation (not recommended)
  • Severe hepatic impairment

Interaction

  • Diclofenac: Increases plasma levels of lithium, digoxin, methotrexate; enhances anticoagulant activity.
  • Serratiopeptidase: May enhance effects of anticoagulants and antiplatelet drugs.

Warning and Precautions

  • Monitor liver function during prolonged therapy.
  • Use with caution in renal impairment.
  • Avoid alcohol due to hepatotoxicity risk.

Dosage

As directed by the Physician.