Desogestrel Tablets

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Therapeutic Indication

Oral contraception (birth control)
Regulation of menstrual cycle
Treatment of dysmenorrhea
Management of hormonal imbalance
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Desogestrel

Tablet

Desogestrel is a synthetic progestogen used in oral contraceptives. It prevents pregnancy by inhibiting ovulation, thickening cervical mucus to block sperm penetration, and stabilizing the endometrium. It is often combined with ethinylestradiol in combined oral contraceptives.

Speciality Gynaecology
Tags Women’s Health | PCOS | Hormonal Therapy | Contraception
Strength
  • 0.15 mg
Packing Size
  • 21 Tablets

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Mechanism

Desogestrel is converted to etonogestrel, which inhibits ovulation by suppressing gonadotropin release. It also thickens cervical mucus, preventing sperm penetration, and stabilizes the endometrium to reduce breakthrough bleeding.

Pharmacokinetics

  • Absorption: Rapidly absorbed after oral administration.
  • Distribution: Binds to sex hormone-binding globulin (SHBG) and albumin.
  • Metabolism: Converted in the liver to active metabolite etonogestrel.
  • Elimination: Excreted via urine and feces.
  • Half-life: Etonogestrel ~30 hours.

Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Weight changes
  • Mood changes
  • Breakthrough bleeding

Contraindication

  • Not recommended in smokers above 35 years
  • Severe liver disease
  • History of thromboembolic disorders

Interaction

  • Antiepileptic drugs (phenytoin, carbamazepine)
  • Rifampicin and enzyme inducers
  • Certain antibiotics
  • Herbal supplements like St. John’s Wort

Warning and Precautions

  • Not recommended for smokers above 35 years
  • Monitor blood pressure regularly
  • Risk of blood clots with prolonged use
  • Regular gynecological check-up advised

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.