Coral Calcium + Vitamin D3 Tablets

Mechanism

Coral Calcium replenishes calcium and trace minerals, while Vitamin D3 facilitates calcium absorption in the intestine and promotes bone mineralization.

Pharmacokinetics

• Absorption: Calcium absorbed in the small intestine; Vitamin D3 absorbed with dietary fat.
• Distribution: Calcium distributed to bones and teeth; Vitamin D3 stored in fat and liver.
• Metabolism: Vitamin D3 metabolized in liver to calcidiol, then in kidney to calcitriol (active form).
• Excretion: Calcium excreted via urine and feces; Vitamin D3 metabolites excreted in bile.
• Half-life: Vitamin D3 ~15 days; Calcium turnover depends on bone metabolism.

Side Effects

• Constipation
• Nausea
• Hypercalcemia (rare, with overdose)
• Kidney stones (long-term excess use)

Contraindication

• Hypercalcemia
• Renal calculi
• Vitamin D toxicity

Interaction

• Thiazide diuretics (increase risk of hypercalcemia)
• Glucocorticoids (reduce calcium absorption)
• Anticonvulsants (increase Vitamin D metabolism)
• Digitalis (risk of arrhythmias with hypercalcemia)

Warning and Precautions

• Monitor serum calcium and Vitamin D levels during prolonged therapy.
• Use cautiously in patients with renal impairment.
• Excessive intake may cause hypercalcemia and kidney stones.
• Ensure adequate hydration to reduce risk of renal complications.
• Not recommended for patients with known hypersensitivity to calcium or Vitamin D3.

Dosage

As directed by the Dietician.