Citicoline +
Piracetam Tablet

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Therapeutic Indication

Memory loss and cognitive impairment
Stroke recovery
Alzheimer’s disease
Parkinsonism
Age-related cognitive decline
Neurological disorders
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Citicoline + Piracetam

Tablet

The combination contains citicoline and piracetam which is generally prescribed for memory enhancement, neurological and cognitive disorder, Parkinsonism and Alzheimer disorder. These drugs are nutrients and acts as cognition enhancing supplements, and are recommended as part of treatment regimens at some aging clinics. Citicoline has been shown to improve memory and other cognitive functions in patients with chronic cerebrovascular disease or dementia and in old people suffering from memory deficit. Piracetam is a drug which enhances cognition and memory, slows brain aging, increases oxygen and blood flow to the brain, improves Alzheimer's and aids in stroke recovery and related conditions. Piracetam and citicoline stimulate thought without peripheral nervous system stimulation. Citicoline alone gives a lift and then a depression but not when taken along with piracetam. Whereas piracetam induced headache is reduced when taken along with citicoline.

Speciality Neuroprotective Agent
Tags Brain Health | Cognitive Care
Strength
  • Citicoline 500 mg
  • Piracetam 500 mg
Packing Size
  • 10 Tablets

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Mechanism

Citicoline enhances neuronal membrane repair and increases acetylcholine synthesis, improving memory and cognition. Piracetam improves cerebral blood flow, enhances oxygen utilization, and supports neuronal function, resulting in improved learning and mental performance.

Pharmacokinetics

  • Absorption: Both Citicoline and Piracetam are well absorbed after oral administration with high bioavailability.
  • Distribution: Citicoline distributes widely in brain tissues and integrates into cell membranes, while Piracetam crosses the blood-brain barrier effectively.
  • Metabolism: Citicoline is metabolized into choline and cytidine, which participate in phospholipid synthesis. Piracetam undergoes minimal metabolism.
  • Elimination: Piracetam is primarily excreted unchanged via kidneys, whereas Citicoline metabolites are eliminated through urine and respiration.

Side Effects

  • Nervousness or restlessness
  • Weight gain
  • Gastrointestinal discomfort
  • Diarrhea
  • Hypotension

Contraindication

  • Active liver disease
  • Pregnancy & lactation
  • Hypersensitivity to components

Interaction

  • May enhance effects of anticoagulants (increased bleeding risk)
  • Caution with thyroid hormones (may cause confusion or irritability)
  • May interact with CNS stimulants or depressants
  • Use carefully with antihypertensive drugs (may lower blood pressure further)

Warning and Precautions

  • Monitor liver function regularly.
  • Use cautiously in patients with liver disease.
  • Risk of myopathy/rhabdomyolysis.
  • Avoid alcohol consumption.