Ciprofloxacin Tablets

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Therapeutic Indication

Urinary tract infections
Respiratory tract infections
Gastrointestinal infections
Skin and soft tissue infections
Bone and joint infections
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Ciprofloxacin

Tablet

Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a variety of bacterial infections including urinary tract infections, respiratory tract infections, gastrointestinal infections, and certain types of skin infections.

Speciality Internal Medicine | Infectious Diseases | Pulmonology | Urology
Tags Antibiotic | Fluoroquinolone | Broad-spectrum | Antibacterial
Strength
  • 250 mg
  • 500 mg
Packing Size
  • 10 Tablets

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Mechanism

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription, leading to bacterial cell death.

Pharmacokinetics

  • Absorption: Rapidly absorbed orally.
  • Metabolism: Partially metabolized in liver.
  • Excretion: Mainly via urine and feces.
  • Half-life: ~4 hours.

Side Effects

  • Nausea, vomiting, diarrhea
  • Dizziness, headache
  • Photosensitivity
  • Rare: tendon rupture, CNS effects

Contraindication

  • Hypersensitivity to fluoroquinolones
  • Pregnancy and lactation (unless essential)
  • Children/adolescents (risk of cartilage damage)

Interaction

  • Antacids (reduce absorption)
  • Theophylline (increased levels)
  • Warfarin (enhanced anticoagulant effect)

Warning and Precautions

  • Use with caution in renal impairment
  • Avoid excessive sun exposure
  • Monitor for tendon pain or swelling
  • Not recommended during pregnancy unless essential

Dosage

As directed by the Physician.