Cetirizine Tablets

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Therapeutic Indication

Allergic rhinitis (seasonal & perennial)
Hay fever
Chronic urticaria (hives)
Skin allergies and itching
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Cetirizine

Tablet

Cetirizine is a second-generation antihistamine used to relieve allergy symptoms such as sneezing, runny nose, watery eyes, and itching. It works by selectively blocking peripheral H1 receptors, reducing histamine-mediated allergic responses.

Speciality Allergy | Immunology | Dermatology | General Medicine
Tags Antihistamine | Allergy Relief | Urticaria Treatment
Strength
  • 10 mg
Packing Size
  • 10 Tablets

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Mechanism

Cetirizine selectively blocks peripheral H1 histamine receptors, preventing histamine from binding and triggering allergic symptoms. Unlike first-generation antihistamines, it causes minimal sedation.

Pharmacokinetics

  • Absorption: Rapidly absorbed; peak plasma concentration ~1 hour.
  • Distribution: 93% plasma protein binding.
  • Metabolism: Minimal hepatic metabolism.
  • Excretion: 70% via urine, 10% via feces.
  • Half-life: ~8.3 hours.

Side Effects

  • Headache
  • Sleepiness
  • Dry mouth
  • Nausea

Contraindication

  • Hypersensitivity to cetirizine or hydroxyzine
  • Pregnancy and lactation (use with caution)

Interaction

  • Theophylline (reduces clearance of cetirizine)
  • Sedatives/tranquilizers (additive drowsiness)

Warning and Precautions

  • Use under medical supervision only
  • Caution in patients with renal impairment
  • Avoid alcohol and CNS depressants

Dosage

As directed by the Physician.