Cetirizine + Ambroxol Tablets

Therapeutic Indication

Allergic rhinitis and hay fever

Chronic urticaria (hives)

Cough associated with respiratory tract infections

Bronchitis with mucus congestion

Skin allergies and itching

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Cetirizine + Ambroxol

Tablet

Cetirizine is a second-generation antihistamine that relieves allergy symptoms, while Ambroxol is a mucolytic agent that thins and loosens mucus in the airways. Together, they provide relief from allergic conditions and respiratory tract congestion.

Speciality	Allergy \| Pulmonology \| Dermatology \| General Medicine
Tags	Antihistamine \| Mucolytic \| Allergy Relief \| Cough Relief
Strength	Cetirizine 5 mg Ambroxol 60 mg
Packing Size	10 Tablets

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Mechanism

Cetirizine blocks peripheral H1 histamine receptors, reducing allergic symptoms. Ambroxol enhances mucus clearance by breaking down mucopolysaccharide fibers, improving expectoration and easing breathing.

Pharmacokinetics

Cetirizine: Rapid absorption; peak plasma concentration ~1 hour; half-life ~8 hours; excreted mainly via urine.
Ambroxol: Absorbed in GI tract; peak plasma concentration ~2 hours; metabolized in liver; half-life ~10 hours; excreted via urine.

Side Effects

Headache
Sleepiness
Dry mouth
Nausea
Gastrointestinal discomfort

Contraindication

Hypersensitivity to cetirizine or ambroxol
Pregnancy and lactation (use with caution)
Severe hepatic or renal impairment

Interaction

Sedatives/tranquilizers (additive drowsiness with cetirizine)
Antibiotics (ambroxol may enhance penetration into lung tissue)

Warning and Precautions

Use under medical supervision only
Caution in patients with renal or hepatic impairment
Avoid alcohol and CNS depressants

Dosage

As directed by the Physician.