Cefixime + Dicloxacillin Tablets

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Therapeutic Indication

Respiratory tract infections
Urinary tract infections
Skin and soft tissue infections
ENT infections
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Cefixime + Dicloxacillin

Tablet

Cefixime is a third-generation cephalosporin antibiotic, while Dicloxacillin is a penicillinase-resistant penicillin. Together, they provide broad-spectrum coverage against Gram-positive and Gram-negative bacteria, useful in resistant infections.

Speciality Internal Medicine | Pediatrics | Dermatology | ENT
Tags Antibiotic | Cephalosporin | Penicillin | Broad-spectrum | Antibacterial
Strength
  • Cefixime 200 mg
  • Dicloxacillin 500 mg
Packing Size
  • 10 Tablets

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Mechanism

Cefixime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, while Dicloxacillin resists beta-lactamase degradation and targets Gram-positive bacteria, enhancing combined efficacy.

Pharmacokinetics

  • Absorption: Cefixime moderately absorbed; Dicloxacillin well absorbed orally.
  • Metabolism: Minimal hepatic metabolism.
  • Excretion: Primarily via urine.
  • Half-life: Cefixime ~3–4 hours; Dicloxacillin ~0.5–1 hour.

Side Effects

  • Nausea, vomiting, diarrhea
  • Skin rash
  • Allergic reactions
  • Rare: anaphylaxis, liver enzyme elevation

Contraindication

  • Hypersensitivity to cefixime, dicloxacillin, cephalosporins, or penicillins
  • History of severe hypersensitivity reactions to beta-lactam antibiotics
  • Previous severe antibiotic-associated allergic reactions

Interaction

  • Warfarin (increased anticoagulant effect)
  • Probenecid (increased antibiotic levels)
  • Oral contraceptives (reduced efficacy)

Warning and Precautions

  • Use with caution in renal impairment
  • Monitor for allergic reactions
  • Not recommended during pregnancy unless essential
  • Complete full course to avoid resistance

Dosage

As directed by the Physician.

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.