Cefdinir Tablets

Therapeutic Indication

Respiratory tract infections (bronchitis, pneumonia)

Ear infections (otitis media)

Skin and soft tissue infections

Sinusitis and pharyngitis

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Cefdinir

Tablet

Cefdinir is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death.

Speciality	Infectious Diseases
Tags	Antibiotic \| Cephalosporin \| Respiratory \| Skin Infections
Strength	250 mg
Packing Size	10 Tablets

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Mechanism

Cefdinir binds to penicillin-binding proteins (PBPs) in bacterial cell walls, inhibiting peptidoglycan synthesis. This weakens the cell wall and causes bacterial cell death.

Pharmacokinetics

Absorption: Moderately absorbed orally (~20–25%).
Distribution: Widely distributed in tissues and fluids.
Metabolism: Minimal hepatic metabolism.
Elimination: Primarily renal excretion.
Half-life: ~1.7 hours.

Side Effects

Diarrhea
Nausea, vomiting
Skin rash
Headache
Rare: Clostridium difficile-associated diarrhea

Contraindication

Hypersensitivity to cephalosporins or penicillins
History of severe allergic reactions
Use with caution in renal impairment

Interaction

Antacids containing aluminum or magnesium (reduce absorption)
Iron supplements (reduce absorption)
Probenecid (increases cefdinir levels)

Warning and Precautions

Use under medical supervision
Adjust dose in renal impairment
Monitor for signs of allergic reaction
Not effective against viral infections

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.