Candesartan + Hydrochlorothiazide Tablets

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Therapeutic Indication

Hypertension (high blood pressure)
Cardiovascular disease prevention
Patients requiring combination therapy for BP control
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Candesartan + Hydrochlorothiazide

Tablet

This combination medicine lowers blood pressure by blocking angiotensin II receptors (Candesartan) and promoting diuresis (Hydrochlorothiazide). It is prescribed for patients with hypertension to reduce the risk of stroke, heart attack, and kidney damage.

Speciality Cardiology | Internal Medicine
Tags Cardiac Care | Hypertension Control
Strength
  • Candesartan 16 mg
  • Hydrochlorothiazide 12.5 mg
Packing Size
  • 10 Tablets

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Mechanism

Candesartan blocks angiotensin II receptors, preventing vasoconstriction and lowering blood pressure. Hydrochlorothiazide increases urinary excretion of sodium and water, reducing blood volume. Together, they provide effective antihypertensive control.

Pharamcokinetics

  • Absorption: Well absorbed orally
  • Distribution: Protein-bound
  • Metabolism: Hepatic metabolism
  • Elimination: Renal excretion
  • Half-life: Candesartan ~9 hrs, Hydrochlorothiazide ~6-15 hrs

    • Side Effects

    • Dizziness
    • Fatigue
    • Electrolyte imbalance (low potassium, sodium)
    • Increased urination
    • Hypotension

    Contraindication

    • Severe kidney disease
    • Pregnancy and breastfeeding
    • Hypersensitivity to sulfonamides
    • Children under 18 years

    Interaction

    • Other antihypertensives (risk of hypotension)
    • NSAIDs (reduced efficacy, kidney risk)
    • Potassium supplements or sparing diuretics (risk of hyperkalemia)
    • Alcohol (enhanced BP lowering effect)

    Warning and Precautions

    • Monitor blood pressure regularly
    • Check electrolytes (potassium, sodium)
    • Use with caution in elderly patients
    • Avoid dehydration during therapy

    Dosage

    As directed by the Physician.

    Disclaimer

    All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
    As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
    Please consult a healthcare professional before using any medicinal product.