Brivaracetam Tablets

Therapeutic Indication

Partial-Onset Seizures

Epilepsy (Adjunctive Therapy)

Brivaracetam

Tablet

Brivaracetam is an anticonvulsant medication used to treat partial-onset seizures in patients with epilepsy. It works by binding selectively to synaptic vesicle protein 2A (SV2A), reducing neuronal hyperexcitability.

Speciality	Neurology
Tags	Epilepsy \| Seizures \| Anticonvulsant
Strength	10 mg 25 mg 50 mg 75 mg 100 mg
Packing Size	10 Tablets

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Mechanism

Brivaracetam binds to SV2A in the brain, modulating neurotransmitter release and reducing seizure activity.

Pharmacokinetics

Absorption: Rapid oral absorption.
Metabolism: Liver metabolism via CYP2C19.
Excretion: Primarily via urine.
Half-life: ~9 hours.

Side Effects

Somnolence
Dizziness
Fatigue
Nausea
Irritability
Suicidal thoughts (rare)

Contraindication

Hypersensitivity to Brivaracetam
Severe hepatic impairment (dose adjustment required)

Interaction

Carbamazepine (may increase dizziness)
Alcohol (enhanced sedation)
Other antiepileptics (monitor plasma levels)

Warning and Precautions

Monitor for psychiatric symptoms (depression, suicidal ideation).
Do not stop abruptly; taper under medical supervision.
Use caution with hepatic impairment.

Dosage

As directed by the Physician.

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