Bilastine + Montelukast Tablets

Project Image
Thumb Image

Therapeutic Indication

Allergic rhinitis (seasonal & perennial)
Asthma (as adjunct therapy)
Urticaria (hives, itching)
Allergic conjunctivitis
+91 85919 78885

Bilastine + Montelukast

Tablet

A modern anti-allergic combination containing Bilastine, a second-generation antihistamine, and Montelukast, a leukotriene receptor antagonist, designed to provide effective relief from allergic symptoms associated with allergic rhinitis and related respiratory allergies.

Speciality Seasonal allergies | Pulmonology | ENT | Dermatology
Tags Perennial allergic rhinitis | Antihistamine | Leukotriene Antagonist | Allergy Relief
Strength
  • Bilastine 20 mg
  • Montelukast 10 mg
Packing Size
  • 10 Tablets

Check all Tablet Range

Click to know More

Mechanism

Bilastine is a non-sedating second-generation antihistamine that selectively blocks peripheral H1 receptors, helping relieve symptoms such as sneezing, nasal discharge, itching, and watery eyes. Montelukast is a leukotriene receptor antagonist that blocks leukotrienes, inflammatory substances responsible for airway inflammation, nasal congestion, and allergic symptoms. Together, they provide comprehensive control of allergic manifestations.

Pharmacokinetics

  • Absorption: Bilastine rapidly absorbed; Montelukast bioavailability ~64%.
  • Distribution: Both highly protein bound.
  • Metabolism: Bilastine minimal hepatic metabolism; Montelukast via CYP3A4.
  • Elimination: Bilastine fecal; Montelukast renal and fecal.
  • Half-life: Bilastine ~14 hrs; Montelukast ~2.7–5.5 hrs.

Side Effects

  • Drowsiness (rare with Bilastine)
  • Headache
  • Abdominal pain
  • Diarrhea
  • Fatigue

Contraindication

  • Hypersensitivity to Bilastine or Montelukast
  • Severe hepatic impairment
  • Pregnancy and lactation (use with caution)

Interaction

  • CYP3A4 inducers (rifampicin, phenytoin reduce Montelukast efficacy)
  • Alcohol (may increase drowsiness)
  • Other antihistamines (additive effect)

Warning and Precautions

  • Use under medical supervision only
  • Monitor liver function during therapy
  • Not recommended for acute asthma attacks

Dosage

As directed by the Physician.