Rosuvastatin + Fenofibrate Tablets

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Therapeutic Indication

Mixed dyslipidemia (high cholesterol + triglycerides)
Hypercholesterolemia
Hypertriglyceridemia
Cardiovascular disease prevention
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Atorvastatin + Fenofibrate

Tablet

This combination medicine lowers LDL cholesterol and triglycerides while raising HDL cholesterol. It is prescribed for patients with mixed lipid disorders to reduce the risk of heart attack, stroke, and atherosclerosis.

Speciality Cardiology | Internal Medicine
Tags Cardiac Care | Lipid Control
Strength
  • Atorvastatin 10 mg
  • Fenofibrate 160 mg
Packing Size
  • 10 Tablets

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Mechanism

Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis in the liver. Fenofibrate activates PPAR-α receptors, lowering triglycerides and increasing HDL cholesterol. Together, they improve overall lipid profile.

Pharamcokinetics

  • Absorption: Well absorbed orally
  • Distribution: Highly protein-bound
  • Metabolism: Hepatic metabolism (CYP enzymes)
  • Elimination: Renal and fecal excretion
  • Half-life: Atorvastatin ~14 hrs, Fenofibrate ~20 hrs
  • Side Effects

    • Headache
    • Stomach pain
    • Diarrhea
    • Muscle pain or weakness
    • Liver enzyme elevation

    Contraindication

    • Severe liver or kidney disease
    • Gallbladder disease
    • Pregnancy and breastfeeding
    • Children under 18 years

    Interaction

    • Other statins (risk of muscle toxicity)
    • Anticoagulants (warfarin, clopidogrel)
    • Alcohol and hepatotoxic drugs
    • CYP3A4 inhibitors (erythromycin, ketoconazole)

    Warning and Precautions

    • Monitor liver function regularly
    • Check for muscle pain or weakness (risk of rhabdomyolysis)
    • Use with caution in elderly patients
    • Avoid alcohol during therapy

    Dosage

    As directed by the Physician.

    Disclaimer

    All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
    As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
    Please consult a healthcare professional before using any medicinal product.