Ademetionine Tablets

Therapeutic Indication

Liver disease (cholestasis, fatty liver)

Depression (adjunct therapy)

Osteoarthritis & fibromyalgia

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Ademetionine

Tablet

Ademetionine (S‑adenosylmethionine) is a naturally occurring compound with hepatoprotective, antidepressant, and anti‑inflammatory properties. It is used in chronic liver disease, depression, osteoarthritis, and fibromyalgia.

Speciality	Gastroenterology \| Psychiatry \| Orthopedics
Tags	Hepatoprotective \| Antidepressant \| Anti‑inflammatory
Strength	400 mg
Packing Size	10 Tablets

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Mechanism

Ademetionine replenishes S‑adenosylmethionine levels in the body, supporting methylation reactions, glutathione synthesis, and neurotransmitter regulation. This improves liver detoxification and mood balance.

Pharmacokinetics

Absorption: Best on empty stomach.
Distribution: Crosses blood‑brain barrier.
Metabolism: Extensively metabolized in the liver.
Elimination: Excreted via urine and bile.
Half-life: 1.5–3.5 hours.

Side Effects

Headache
Nausea
Dizziness
Dry mouth
Stomach pain

Contraindication

Bipolar disorder (risk of mania)
Hypersensitivity to ademetionine
Pregnancy & breastfeeding (unless necessary)

Interaction

MAO inhibitors (risk of serotonin syndrome)
Other antidepressants (additive effect)

Warning and Precautions

Take on empty stomach for better absorption
Use cautiously in kidney disease
Monitor mood in psychiatric patients

Dosage

As directed by the Physician.

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As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.