Aceclofenac + Thiocolchicoside Tablets

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Therapeutic Indication

Musculoskeletal pain
Inflammation and swelling
Muscle spasms (back pain, neck pain)
Arthritis and joint pain
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Aceclofenac + Thiocolchicoside

Tablet

This combination medicine provides dual action: Aceclofenac reduces pain and inflammation, while Thiocolchicoside relaxes muscles and relieves spasms. It is commonly prescribed for acute musculoskeletal conditions.

Speciality Orthopedics | Pain Management | Rheumatology
Tags NSAID | Muscle Relaxant | Pain Relief
Strength
  • Aceclofenac 100 mg
  • Thiocolchicoside 4 mg/8 mg
Packing Size
  • 10 Tablets

Mechanism

Aceclofenac inhibits prostaglandin synthesis, reducing inflammation and pain. Thiocolchicoside acts on GABA receptors, relaxing skeletal muscles and reducing spasms.

Pharmacokinetics

  • Absorption: Rapid oral absorption.
  • Distribution: Widely distributed.
  • Metabolism: Hepatic metabolism.
  • Elimination: Renal and fecal excretion.
  • Half-life: Aceclofenac ~4 hrs; Thiocolchicoside ~5–6 hrs.

Side Effects

  • Gastric irritation, nausea
  • Drowsiness, diarrhea
  • Rare: liver toxicity

Contraindication

  • Severe liver or kidney disease
  • History of gastric ulcers
  • Pregnancy & breastfeeding (Thiocolchicoside contraindicated)
  • Hypersensitivity to NSAIDs

Interaction

  • Alcohol: Increases risk of gastric bleeding and liver damage.
  • Anticoagulants: Aceclofenac may enhance bleeding risk.
  • Other NSAIDs: Avoid duplication of therapy.

Warning and Precautions

  • Do not exceed recommended dose.
  • Use cautiously in patients with GI disorders.
  • Monitor liver function during prolonged use.

Dosage

As directed by the Physician.