Aceclofenac + Paracetamol + Thiocolchicoside Tablets

Therapeutic Indication

Musculoskeletal pain

Inflammation and swelling

Muscle spasms (back pain, neck pain)

Arthritis and joint pain

Post-surgical pain

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Aceclofenac + Paracetamol + Thiocolchicoside

Tablet

This triple combination medicine provides comprehensive relief: Aceclofenac reduces inflammation and pain, Paracetamol lowers fever and enhances analgesia, while Thiocolchicoside relaxes muscles and relieves spasms. It is prescribed for acute musculoskeletal conditions.

Speciality	Orthopedics \| Pain Management \| Rheumatology
Tags	NSAID \| Analgesic \| Muscle Relaxant \| Pain Relief
Strength	Aceclofenac 100 mg Paracetamol 325 mg Thiocolchicoside 4 mg
Packing Size	10 Tablets

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Mechanism

Aceclofenac inhibits prostaglandin synthesis, reducing inflammation and pain. Thiocolchicoside acts on GABA receptors, relaxing skeletal muscles and reducing spasms.

Pharmacokinetics

Absorption: Rapid oral absorption.
Distribution: Widely distributed.
Metabolism: Hepatic metabolism.
Elimination: Renal and fecal excretion.
Half-life: Aceclofenac ~4 hrs; Paracetamol ~2–3 hrs; Thiocolchicoside ~5–6 hrs.

Side Effects

Gastric irritation, nausea
Drowsiness, diarrhea
Rare: liver toxicity (especially with overdose)

Contraindication

Severe liver or kidney disease
History of gastric ulcers
Pregnancy & breastfeeding (Thiocolchicoside contraindicated)
Hypersensitivity to NSAIDs or paracetamol

Interaction

Alcohol: Increases risk of gastric bleeding and liver damage.
Anticoagulants: Aceclofenac and Paracetamol may enhance bleeding risk.
Other NSAIDs: Avoid duplication of therapy.

Warning and Precautions

Do not exceed recommended dose.
Use cautiously in patients with GI disorders.
Monitor liver function during prolonged use.
Check for hidden paracetamol in combination medicines.

Dosage

As directed by the Physician.