Acarbose Metformin Tablets

Therapeutic Indication

Management of type 2 diabetes mellitus

Improves glycemic control when diet and exercise are insufficient

Reduces postprandial hyperglycemia

Helps in insulin resistance and metabolic syndrome

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Acarbose + Metformin

Tablet

Acarbose is an alpha-glucosidase inhibitor that delays carbohydrate absorption, while Metformin improves insulin sensitivity and reduces hepatic glucose production. Together, they provide synergistic control of blood glucose in type 2 diabetes.

Speciality	Endocrinology \| Internal Medicine \| Diabetology
Tags	Antidiabetic \| Glycemic Control \| Insulin Sensitizer
Strength	Acarbose 25 mg Metformin Hydrochloride 50 mg
Packing Size	10 Tablets

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Mechanism

Acarbose inhibits intestinal alpha-glucosidase enzymes, delaying carbohydrate breakdown and absorption. Metformin decreases hepatic glucose production, enhances insulin sensitivity, and improves peripheral glucose uptake.

Pharmacokinetics

Absorption: Acarbose minimally absorbed; Metformin absorbed in small intestine.
Metabolism: Acarbose metabolized by intestinal bacteria; Metformin not metabolized significantly.
Excretion: Acarbose via feces; Metformin excreted unchanged via urine.

Side Effects

Flatulence and abdominal discomfort (Acarbose)
Diarrhea and nausea (Metformin)
Rare: Lactic acidosis (Metformin)

Contraindication

Severe renal impairment
Hepatic dysfunction
Gastrointestinal disorders (for Acarbose)
Hypersensitivity to components

Interaction

Alcohol (increases risk of lactic acidosis with Metformin)
Insulin or sulfonylureas (risk of hypoglycemia)
Antibiotics (may alter Acarbose efficacy)
Cationic drugs (reduce Metformin clearance)

Warning and Precautions

Monitor renal function regularly
Discontinue before radiological procedures with contrast agents
Use cautiously in elderly patients

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.

Acarbose + Metformin Tablets