Advanced Formula for Healthy Hair Tablets

Mechanism

• Vitamins
• Vitamin A (Beta Carotene): Vitamin A is responsible for secreting oil which makes hairs shiny and lustrous. Deficiency of Vitamin A leads to dry scalp and dandruff. But these problems can be prevented by taking vitamin A supplement. This vitamin protects hair follicle cells from damage caused by free radicals. Vitamin A deficiency causes dry hair.
  Niacinamide: It is one of the forms of Vitamin B3. And it promotes the hair growth by increasing the blood circulation to the scalp. It shows best results when combine with Biotin. Reduced levels of niacin amide can attribute to poor nourishment to hair follicles.
  Biotin: Biotin, also known as vitamin H is a micronutrient that is be essential for maintaining healthy hair and skin.
  (According to some source the H actually stands for "haar and haut" German for "hair and skin").
  Biotin is absorbed into the shafts of hair, where it "moderates the damage environmental or other factors may have caused, and increases the diameter of the hair shafts." Biotin deficiency in humans and animals causes pathological changes in the skin and its appendages such as desqamative dermatitis and alopecia. Biotin acts as an essential cofactor for the acetyl-CoA, propionyl-CoA, ß-methylcrotonyl-CoA and pyruvate carboxylase enzymes, which are important in the synthesis of fatty acids, the catabolism of branched-chain amino acids and the gluconeogenic pathway. Biotin may also have a role in the regulation of gene expression arising from its interaction with nuclear histone proteins.
  Vitamin E: Vitamin E consists of eight similar compounds- four tocotrienols and four tocophenols whilst tocopherols had been intensively studied for their benefits, many unique benefits of tocotrienols.
  
  These novel health benefits include:
  • Hair loss prevention
  • Potent antioxidant
  • Skin protection
  • Cardiovascular protection
  • Neuroprotective
  • Anticancer effects
  It promotes scalp circulation by increasing oxygen intake; it also combats the effects of free radicals and cell aging, thereby promoting healthy hair and scalp.
  Folic Acid: It is a water soluble vitamin B. It is essential for human body to synthesize DNA and repair DNA. Decrease in folic acid may contribute to decrease hair-follicle cell division and growth. Folic acid is also essential for maintenance of healthy methionine levels in the body.
  .
• Minerals
• Minerals are the naturally occurring inorganic nutrients that are relevant to human nutrition. Minerals are needed by body in small amount to help it function properly. Without adequate quantity of minerals, our body is not able to absorb other nutrients like vitamins, proteins, carbohydrate. Hair loss is often indicative of deficiency of minerals in human body.
  Calcium: Calcium is the body's most abundant mineral-about 2% of body weight is calcium in bones and teeth. A little is scattered in soft tissue like muscles and organs. Calcium is bone builder, but also needed to move muscles, clot blood and fire nerves. Most calcium comes from dairy foods like milk, cheese and yogurt. Calcium stimulates cell mediators that act on cell- membrane phospholipids in hair-follicle. Calcium is an important mineral for hair growth because hair follicles use calcium to make keratinized protein that keeps hair shiny, healthy and strong.
  Magnesium: Calcium and magnesium complement one another. Calcium provides strength; magnesium provides elasticity to prevent injury. Magnesium also works with calcium to assist in muscle contraction, blood clotting and the regulation of blood pressure and lung function.
  Magnesium is a cofactor in many enzyme reactions that regulate protein synthesis. Magnesium also plays an important role in transport of calcium which is essential for healthy hairs.
  Iron: An iron deficiency can cause women's body to stop producing hairs. Iron is present in red blood cells that carry oxygen to every cell and hence promote hair growth by enhancing blood circulation to the scalp.
  Zinc: Zinc is essential for DNA and RNA production, which, in turn, leads to normal follicle-cell division. Zinc is also responsible for helping to stabilize cell-membrane structure 18 and assists in the breakdown and removal of superoxide radicals, thereby aiding in the healthy follicle promotion and aids in improvement in hair loss.
  Copper: Free radicals are responsible for cell damage. Copper act as anti-oxidant that helps in free radical scavenging and prevent hair loss.
  Manganese: It is trace mineral that is present in very small amount in body. It helps in absorbing calcium that makes hair strong. It also acts as antioxidant.
  Selenium: Selenium functions primarily as an activator of enzymes necessary for protection from oxidative damage to the tissue and maintaining normal redox potentials in the cells. The enzyme glutathione reductase is especially important in this regards it keeps glutathione available for guarding against damage from oxidizers like superoxide radicals. Protection against the oxidative damage results in shiny hair and healthy hair follicles.
• Natural Extracts
• Soya Isoflavones: Soybeans are a rich source of flavonoids, which form a large group of plant polyphenols that are divided into anthocyanins, flavones, flavonols, and isoflavones. The anthocyanins are responsible for the blue to red colors present in flowers and fruits. The flavones, flavonols, and isoflavones are colorless to yellow and are biologically active compounds that can function as antioxidants, as well as inhibit enzyme function through receptor binding.
  Soy flavonoids also undergo this chemical reaction when administered orally. The flavonoid found in the highest concentration in soy is genistin, which is present in the glycoside's inactive form. The flavonoid can be converted to its aglycon form, the molecular form without the sugar, in the intestine, becoming the potent protein kinase inhibitor genistein. Protein kinase is important cell-signalling pathways in the skin that can lead to the expression of enzymes that degrade collagen and elastin and other scalp hair protein which in turn makes hair follicles weak. Matrix metalloproteinase, activated by oxygen radicals and inflammatory cytokines, are an excellent example of these enzymes.
  Natural extracts containing isoflavone can be administer either orally or topically to prevent hair loss. Isoflavone also exhibit estrogenic activity which prevent hair loss effect of testosterone by inhibiting the binding of testosterone to the hair and scalp receptor, thereby resulting in maintenance of scalp hair integrity. Soya isoflavone extract is use to prevent hair loss both in man and women. Soya isoflavones reduce the level of DHT and increase the number of hair follicles.
  In addition to these benefits, soya isoflavone cause darkening of the hair and also promotes hair growth by enhancing the blood flow in scalp.
  Grape Seed Extract: It is derived from the ground seeds of red wine grapes. Grape seed extract is a mixture of tannin and procyanidins. Extracts of green seed are a great reservoir of natural antioxidants such as vitamin E, and flavones.
  The mechanism by which it prevents hair loss includes: Antioxidant action, which protects the filamentous tissues of the hair from all kind of pollutant and heal the negative effects of free radicals imparting health and repair the damage. It also makes hairs shiny, lustrous, thick, and strong and damage free.
  ● It helps in maintenance of peripheral micro-capillary perfusion, essential for prevention of senescent (age related, non-hormonal) hair loss.
  ● Upregulation of peripheral nitric oxide (NO), a vaso-relaxant.
  ● Down regulation of inflammatory cytokines that have been conclusively implicated in AGA.
  ● Potent free radical scavenging. Grape seed extract is a powerful antioxidant much greater than vitamin C and E. it also inhibits a number of enzymes that degrade connective tissue such as elastase, collagenase and hyaluronidase.
• Amino Acids
• Amino Acids are the Building blocks of the Protein and Proteins are the building blocks of life. They are constantly involved in growth and repair of cells. There are 20 amino acids and these are divided into two categories: Essential and Non-essential amino acids Essential amino acids cannot be produced by body and therefore one needs an external supply for it. Hairs follicles require continue supply of amino acid via blood stream to maintain hair growth.
  There is a simple relationship between amino acids and hair. Amino acids are the building blocks of all the proteins found in the body and hair is composed of keratin, a protein. It is this keratin which gives hair strands their strength. If amino acids are insufficiently supplied to the cells of the hair follicles, the level of keratin production will drop or the keratin produced might lose most of its strength. Both of this will lead to reduced hair growth, discoloured hair and hair strands that easily fall off.
  Glutamic Acid: Glutamine is converted to Glutamic Acid (Glutamate) after it crosses the blood brain barrier. Glutamic acid combines with the amino acid taurine to form GABA (gamma amino butyric acid). GABA regulates neuron firing and neurochemical activity in the brain. Glutamine also serves as a source of fuel for cells.
  Without glutamine the cells would waste away. Glutamine regulates the expression of certain genes and helps regulate the biosynthesis of DNA and RNA. Construction of DNA is dependent upon adequate amounts of glutamine.
  Glutamine promotes healthy hair by above function and by delivering sulphur which is necessary for hair growth.
  DL-Methione: Methione contains sulphur which can build chains, which themselves create networks and this is exactly what happens in hair and nails. Methionine can therefore considerably strengthen the hair structure and nails. Methionine can also help against hair loss.
  Aspartic Acid: Aspartic Acid controls the levels of a variety of amino acids and blood gases that control pH balance and reduce anaerobic activity. Aspartic acid also serves as an excitatory neurotransmitter preventing resistance to fatigue and leading to greater endurance. Aspartic acid provides strength to hairs. It works by increasing steroidogenic acute regulatory protein.
  Leucine: Plasma levels of Leucine manage sugars. However, optimal levels in both Isoleucine and Leucine demonstrate the ability to build sugars and branched amino acids that act as immunological stimulants and nutrients to various glands and endocrine system. This manages the overall competency of the immune system and body. Low levels indicate low immunological response. It gives strengths to hairs.
  Arginine: Arginine causes vasodilatation by increasing level of nitric oxide, which helps to stop hair loss. Nitric oxide formed from Arginine opens the potassium channels of the cells. This can improve the circulation to the hair roots and stimulate hair growth.
  Lysine:Lysine is one of the two most critical amino acids. Plasma levels indicate the degree and extent of overall immunological competency. Lysine is a branched amino acid. This means it is used in the production of every immunological protein, antibody, antigen, hormone, growth factor and cytokine (protein). Low levels indicate deficiencies in overall immunological functioning.
  Serine: Serine is a non-essential amino acid derived from the amino acid Glycine. It is important to overall good health, both physical and mental. Serine helps form the phospholipids needed to make every cell in the body. It is also involved in the function of RNA and DNA, fat and fatty acid metabolism, muscle formation, and the maintenance of a healthy immune system.
  Phenylalanine:It is an amino acid responsible for the pigments of hair. Phenylalanine is an essential amino acid that cannot be produced by the human body, Phenylalanine is necessary for the production of other amino acids that enhance the production of adrenalin. Deficiency or low amounts of same can result into retardation in growth and affecting the hair health.
  Valine:Valine is a neuro-excitory amino acid. Optimal levels are usually present with stable psychology and physiology. Low levels indicate physiological depression.
  Glycine: It is a non essential amino acid and provides protection form damage via antioxidant action. Glycine is a nonessential amino acid and is an important component of collagen, Glycine enhances growth hormone levels. It helps in maintaining healthy scalp skin and in turn promoting hair follicles health.
  Tyrosine: Hair loss can be attributed to a number of reasons, most commonly genetics. According to recent research, three types of hair loss are stress-induced. They include alopecia areata, telogen effluvium and trichotillomania.
  L-tyrosine, so also simply known as tyrosine, is a nonessential amino acid that occurs naturally in your body. The amino acid plays an important role in helping nerve cells communicate properly. The neurotransmitters that influence mood and nerve cells functions are made up of tyrosine building blocks. In addition, tyrosine is vital in regulating hormones in the adrenal, pituitary and thyroid glands.
  High stress levels in a person can cause a drop in the production of tyrosine that, in turn, reduces the amount of stress hormones available to deal with stress-related symptoms and thereby leading to damage in scalp conditions and hair loss.
  Alanine: Alanine is an immune system marker and indicates how effectively the immune system is killing harmful cells. Alanine is also vital for the production of protein, essential for proper function of the central nervous system and growth and helps form neurotransmitters.
  Cystine: Cystine has a number of beneficial effects such as enhancing toxin removal, aiding in the proper functioning of the central nervous system, immune system enhancement, blood pressure regulation, visual acuity, muscle creation, and fat burning. It supports hair health by enhancing toxin removal and growth in follicular cells.
  Tryptophan: Tryptophan plays a key neurological and physiological role by ensuring metabolic stimulation of various chemistry and processes that regulate circadian cycles (wake/sleep states) and all of the attendant circadian activities relative to these cycles. Low levels are usually present with poor wake and sleep states, underwritten by poor chemical and metabolic activities consistent to each state.
  Histidine: L-Histidine includes the regulation of the pH-value of the blood, supporting the healing of wounds, and the regulation of growth and natural repair mechanisms. Without L-Histidine growth processes would be interrupted and a lack of this amino acid can lead to slow development and the regeneration of tissue. It is also possible that a deficiency can lead to the inflammation of the skin and mucous membrane and a slower recovery after operation or surgical procedures. Among other things, L-Histidine is also necessary for the formation of the myelin sheath, which surrounds all nerve cells and protects them from damage, and can be used to prevent certain degenerative conditions, such as Alzheimer's and Parkinson's. Moreover, this semi-essential amino acid is involved in the synthesis of red and white blood cells, and so influence the activity of the immune system, as leukocyte play a large role in combating pathogens. Its growth promoting property in turn aids in hair shaft growth and healthy hair follicles.
  
  The pursuit of health involves taking adequate nutrition and in right amounts, various genetic and physiologic factors can lead to malabsorption of nutrient in turn affecting the overall health of human body, Hairs are first to respond to poor nutrition, Nutritional therapy is an answer to all the problems. It is very difficult in today's world to overcome the stress and improper eating habits, Hair vita is one stop solution for all the problems. It provides all the essential nutrients and the right combination of essential vitamins, minerals and amino acid acts synergistically to provide improved health of not only hair but overall health.
  Nutrient shortfalls have health consequences that could impact daily life and overall wellbeing. Nutritional supplement replenishes the deficient stores.

Pharmacokinetics

• Absorption: Vitamins and minerals absorbed in small intestine.
• Distribution: Biotin and amino acids distributed to hair follicles and scalp tissues.
• Metabolism: Vitamins metabolized in liver; amino acids incorporated into protein synthesis.
• Excretion: Water-soluble vitamins via urine; minerals via urine/feces.

Side Effects

• Mild gastrointestinal upset
• Rare allergic reactions
• Headache or dizziness

Contraindication

• Hypersensitivity to any component
• Pregnancy & lactation (use under medical supervision)
• Severe hepatic or renal impairment

Interaction

• Iron may interact with antacids and tetracyclines.
• Zinc may reduce absorption of certain antibiotics.
• Vitamin E may increase bleeding risk with anticoagulants.

Warning and Precautions

• Monitor patients with bleeding disorders.
• Use with caution in patients on anticoagulants.
• Take with meals for better absorption.

Dosage

As directed by the Physician.