Silymarin with Antioxidants Tablets

Therapeutic Indication

Liver diseases (acute & chronic hepatitis)

Protection from toxins, alcohol, heavy metals

Fatty liver degeneration

Jaundice

Psoriasis, uterine tonic, menstrual difficulties

Spleen, kidney, gall bladder tonic

Varicose veins

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Silymarin with Antioxidants Tablets

Tablet

This combination provides synergistic hepatoprotection and nutritional support. Silymarin stabilizes liver cell membranes and promotes protein synthesis. Added antioxidants (Vitamins, minerals, amino acids) enhance detoxification, reduce oxidative stress, and support overall cellular health.

Speciality	Hepatoprotective \| Herbal Medicine
Tags	Liver Health \| Hepatoprotective \| Milk Thistle Extract
Strength	Silymarin Extract – 140 mg L-Carnitine Tartrate – 5000 mcg N-Acetyl Cysteine – 5000 mcg L-Glutathione – 1500 mcg L-Ornithine Hydrochloride – 5000 mcg Vitamin E – 9 mg Calcium Pantothenate – 8.5 mg Vitamin B1 – 1.6 mg Folic Acid – 0.1 mg Vitamin B12 – 1 mcg Vitamin C – 40 mg Choline Bitartrate – 5000 mcg Vitamin B6 – 1.3 mg Vitamin B2 – 2 mg Vitamin D3 – 9.5 mcg Inositol – 5000 mcg Zinc Sulphate – 10 mg (eqv. 2.274 mg elemental zinc) Ferrous Fumarate – 3 mg (eqv. 0.986 mg elemental iron) Sodium Selenate – 36 mcg (eqv. 15.04 mcg elemental selenium) Coenzyme Q10 – 250 mcg
Packing Size	10 Tablets

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Mechanism

Silymarin acts as a potent antioxidant, stabilizing hepatocyte membranes and enhancing protein synthesis. N-Acetyl Cysteine replenishes glutathione reserves. L-Glutathione and L-Carnitine reduce oxidative stress and support cellular energy. Vitamins and minerals provide additional antioxidant and metabolic support.

Pharmacokinetics

Absorption: Moderate oral absorption; bioavailability varies with formulation
Distribution: Concentrated in liver tissue; moderate plasma protein binding
Metabolism: Hepatic metabolism via conjugation (glucuronidation and sulfation)
Elimination: Primarily biliary excretion; minor renal excretion
Half-life: ≈ 6 hours

Side Effects

Abdominal bloating
Diarrhea
Flatulence
Loss of appetite
Nausea and stomach upset

Contraindication

Hypersensitivity to milk thistle (*Silybum marianum*) or related plants
Pregnancy and lactation — use cautiously, limited safety data
Severe hepatic impairment — not recommended without medical supervision
Children — limited clinical data, use only under physician guidance

Interaction

May alter metabolism of drugs via CYP450 enzymes (e.g., statins, antidepressants)
Potential interaction with hepatotoxic drugs (e.g., methotrexate, acetaminophen)
Use cautiously with anticoagulants — possible additive effect
Alcohol may reduce hepatoprotective efficacy

Warning and Precautions

Monitor liver function during therapy
Use as adjunct therapy, not replacement for medical treatment
Consult physician before long-term use