Oxymetazoline Nasal Spray

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Therapeutic Indication

Nasal congestion in children
Adjunct therapy for relief of Eustachian tube congestion
Common cold & viral rhinitis
Sinusitis-related nasal blockage
Allergic rhinitis (symptomatic relief)
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Oxymetazoline

Nasal Spray

This pediatric nasal spray contains Oxymetazoline, a long-acting topical nasal decongestant specifically formulated for children. It provides rapid and sustained relief from nasal congestion by constricting dilated blood vessels in the nasal mucosa. This reduces swelling, clears blocked nasal passages, and improves airflow, allowing easier breathing.
The lower pediatric strength ensures effective relief with a safer profile when used as directed. The formulation begins to act within minutes and provides prolonged relief (up to 10–12 hours), making it suitable for day and night symptom control during cold and allergy conditions.

Speciality ENT | Pediatric Care
Tags Pediatric Nasal Spray | Long-acting Decongestant | Cold Relief
Strength
  • Oxymetazoline – 0.025% w/v
Packing Size
  • 10 ml Spray Bottle

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Mechanism

Oxymetazoline
Acts as a selective alpha-adrenergic agonist (primarily α1 and partial α2 receptor activity), causing vasoconstriction of arterioles in the nasal mucosa. This leads to reduced blood flow, decreased mucosal edema, and rapid decongestion of nasal passages. The prolonged receptor binding contributes to its long duration of action compared to other decongestants.

Side Effects

  • Dryness of throat or nasal mucosa
  • Rebound congestion (rhinitis medicamentosa) with prolonged or excessive use
  • Sneezing

Contraindication

  • Hypersensitivity to Oxymetazoline or any component
  • Infants below recommended age group (unless prescribed)
  • Narrow-angle glaucoma
  • Recent nasal surgery or injury
  • Severe cardiovascular disorders (use only under medical advice)

Dosage

  • As directed by the physician.

Direction for use

  • Put the cap with spike on the container. Tighten the cap on the nozzle. The spike in the cap will pierce the tip of the container.
  • Dispense drops/spray with gentle pressure. Replace the cap after every use.

DRUG INTERACTIONS

  • MAO inhibitors: May increase risk of hypertensive effects
  • Tricyclic antidepressants: May potentiate vasoconstrictive action
  • Other sympathomimetics: Additive systemic effects
  • Antihypertensive drugs: May reduce effectiveness

Warning and Precautions

  • For nasal use only
  • Use strictly for short duration (max 3–5 days) to avoid rebound congestion
  • Use with caution in children with hypertension, diabetes, thyroid disorders, or heart conditions
  • Avoid spraying into eyes
  • Ensure correct dosing to prevent systemic absorption
  • Keep bottle clean and do not share between individuals
  • Discontinue use if irritation or worsening symptoms occur
  • Store in a cool, dry place
  • Keep out of reach of children

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.