Folic Acid Tablets

Therapeutic Indication

Megaloblastic Anemia due to folate deficiency

Pregnancy supplementation to prevent neural tube defects

General nutritional support

Adjunct therapy in hemolytic anemia

Support in rapid cell division and growth

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Folic Acid

Tablet

Folic acid, also known as folate or Vitamin B9.Folic acid is indicated for the treatment of megaloblastic anaemia because of the folic acid deficiency. Helps prevent folate deficiency in chronic haemolytic states, during renal dialysis, and in drug‑induced deficiency./Adequate amounts of vitamin B12 need to be given along with folic acid.

Folic acid is a vitamin which we use to prevent or treat a deficiency of folic acid in the body. Folic Acid 5mg Tablets is used in the treatment and prevention of certain types of anaemia a low red blood cells. Adequate amounts of vitamin B12 need to be given along with folic acid. Folic acid Tablets can also be given to some women before and during pregnancy to prevent spina bifida an abnormality of the spine in babies, which can be caused by deficiency of this vitamin.

Speciality	Hematology \| Gynecology \| Nutrition \| General Wellness
Tags	Anemia \| Pregnancy Supplement \| Neural Tube Defect Prevention \| DNA Synthesis \| Nutritional Support
Strength	5 mg
Packing Size	10 Tablets

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Mechanism

Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase (DHFR). These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.

Pharmacokinetics

Absorption: Rapidly absorbed in the small intestine.
Distribution: Widely distributed; stored mainly in the liver.
Metabolism: Converted to active tetrahydrofolate in the liver.
Excretion: Primarily via urine; small amounts via bile.
Half-life: 3–4 hours, but tissue stores extend activity.

Side Effects

GI upset (abdominal discomfort)
Nausea
Hypotension (rare)
Allergic reactions (rare)

Contraindication

Known hypersensitivity to folic acid or excipients.
Undiagnosed anemia (risk of masking Vitamin B12 deficiency).
Pernicious anemia (risk of neurological damage).

Interaction

Antifolate drugs (Methotrexate, Trimethoprim, Pyrimethamine) reduce efficacy.
Phenytoin and Carbamazepine may lower folate levels.
Alcohol impairs folate absorption and metabolism.

Warning and Precautions

Do not exceed recommended dosage.
Monitor Vitamin B12 levels to avoid masking deficiency.
Safe in pregnancy when taken as prescribed.
Consult physician before use in chronic illness or concurrent medication.

Dosage

As directed by the Physician.

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Please consult a healthcare professional before using any medicinal product.