Cefpodoxime Tablets

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Therapeutic Indication

Respiratory tract infections (bronchitis, pneumonia)
Urinary tract infections (UTI)
Skin and soft tissue infections
Ear infections (Otitis media)
Sinusitis and tonsillitis
Typhoid fever
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Cefpodoxime

Tablet

Cefpodoxime is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is effective against both Gram-positive and Gram-negative organisms. Cefpodoxime works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. It is commonly prescribed for respiratory tract infections, urinary tract infections, and skin infections, offering reliable efficacy and safety.

Speciality Third Generation Cephalosporin Antibiotic
Tags Antibiotic | Bacterial Infection | Broad Spectrum
Strength
  • 50 mg
  • 100 mg
  • 200 mg
Packing Size
  • 10 Tablets

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Mechanism

Cefpodoxime inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). This disrupts the formation of the bacterial cell wall, leading to cell lysis and death. It is bactericidal in nature and effective against a wide range of pathogens.

Pharmacokinetics

  • Absorption: Well absorbed orally (enhanced with food)
  • Distribution: Widely distributed in body tissues
  • Metabolism: Minimal metabolism
  • Elimination: Primarily excreted via urine
  • Half-life: Approximately 2–3 hours

Side Effects

  • Diarrhea
  • Nausea
  • Abdominal pain
  • Allergic reactions (rash, itching)

Contraindication

  • Hypersensitivity to cephalosporins
  • Severe allergy to penicillin (cross-reactivity risk)

Interaction

  • Antacids (reduce absorption)
  • Probenecid (increases drug levels)
  • Nephrotoxic drugs (increase kidney risk)

Warning and Precautions

  • Use cautiously in renal impairment
  • Complete full antibiotic course
  • Monitor for allergic reactions