CYCLOSPORINE SYRUP | pharmaceutical manufacturing

Therapeutic Indication

Prevention of organ transplant rejection

Rheumatoid arthritis (severe cases)

Psoriasis (severe cases)

Nephrotic syndrome

Autoimmune disorders

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CYCLOSPORINE

Syrup

This oral solution contains Cyclosporine, a potent immunosuppressant used to prevent organ rejection and manage various autoimmune conditions. It works by inhibiting T-lymphocyte activation, thereby reducing immune responses that can damage transplanted organs or cause inflammatory diseases.
Cyclosporine helps maintain graft survival in transplant patients and is also effective in controlling severe autoimmune disorders by suppressing overactive immune responses. The liquid formulation allows precise dosing and ease of administration.

Speciality	Immunology \| Transplant Medicine
Tags	Immunosuppressant \| Transplant Care \| Autoimmune Therapy
Strength	Cyclosporine – 100 mg
Packing Size	50 ml Bottle

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Mechanism

Cyclosporine
Inhibits calcineurin, leading to suppression of interleukin-2 (IL-2) production and T-cell activation, thereby reducing immune response.

Pharmacokinetics

Absorption: Oral absorption.
Distribution: Widely distributed; binds to erythrocytes and plasma proteins.
Metabolism: Hepatic via CYP3A4
Excretion: Primarily biliary
Half‑life: ~8–27 hours

Side Effects

Increased risk of infections
Gum hyperplasia
Tremors

Contraindication

Hypersensitivity to Cyclosporine
Uncontrolled hypertension
Malignancy (relative contraindication)

Dosage

As directed by the physician.

DRUG INTERACTIONS

CYP3A4 inhibitors (e.g., ketoconazole): Increase cyclosporine levels
CYP3A4 inducers (e.g., rifampicin): Decrease levels
Nephrotoxic drugs: Increased risk of kidney damage

Warning and Precautions

Shake well before use
Requires regular monitoring of blood levels
Monitor renal and liver function
Avoid grapefruit juice (may increase drug levels)
Increased risk of infections—avoid exposure
Use under strict medical supervision
Store in a cool, dry place
Keep out of reach of children

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.