Acebrophylline Sustained Release Tablets

Acebrophylline Sustained Release

Tablet

Acebrophylline is a xanthine derivative used as a Bronchodilator in asthma and COPD. It reduces mucus viscosity, improves mucociliary clearance and provides anti-inflammatory action.

Speciality	Bronchodilator | Mucolytic
Tags	Respiratory | Anti-inflammatory
Strength	100 mg 200 mg
Packing	10 Tablets

Mechanism

• Acebrophylline works as a bronchodilator by inhibiting phosphodiesterase
• raising cAMP to relax airway muscles, while its ambroxol part acts as a mucolytic to thin mucus and improve clearance
• together they reduce inflammation by blocking phospholipase A2, TNF‑alpha, and leukotrienes, and also provide antioxidant protection
• making breathing easier in asthma and COPD

Pharmacokinetics

Rapidly absorbed after oral administration. Peak plasma levels occur within 1–2 hours. Metabolized in liver and excreted via kidneys.

Side Effects

• Nausea
• Vomiting
• Headache
• Dizziness
• Skin rash

Contraindication

• Hypersensitivity
• Cardiac arrhythmia
• Severe liver/kidney disease

Interaction

Avoid with erythromycin, cimetidine, quinolones, phenytoin and anticoagulants.

Warning & Precautions

• Use in cardiac patients with caution
• Avoid in peptic ulcer
• Use in pregnancy only if prescribed

Dosage

As directed by the Physician.