Indications: For the symptomatic relief of nasal congestion, perennial and allergic rhinitis (including hay fever), sinusitis.
Mechanism of Action:
Xylometazoline is a sympathomimetic agent acting on alpha-adrenergic receptors in the nasal mucosa.Administered into the nose, it constricts the nasal blood vessels, thereby decongesting the mucosa of the nose and neighbouring regions of the pharynx. This decongests nasal passages and enables patients suffering from blocked nose to breathe more easily through the nose.
Contraindications:
● Known hypersensitivity to the active ingredient or any of the Excipients.
● Patients with trans-sphenoidal hypophysectomy or surgery exposing the dura mater.
Warning & Precautions:
● Patients are advised not to take decongestants for more than seven consecutive days and should be used only with caution in patients showing a strong reaction to sympathomimetic agents as evidenced by signs of insomnia, dizziness etc.
● Caution is recommended in patients with hypertension, cardiovascular disease, hyperthyroidism, narrow angle glaucoma or diabetes mellitus.
Interactions:
As for all sympathomimetics, a reinforcement of the systemic effects of xylometazoline by concomitant use of monoamine oxidase inhibitors, tricyclic or tetracyclic antidepressants, cannot be excluded, especially in case of overdose.
Pregnancy & Lactation:
No foetal toxicity or fertility studies have been reported. If you are pregnant or taking any other medicines or are under a doctor's care, consult him before using Xylometazoline nasal solution.
No evidence of any adverse effect on the breast-fed infant. However, it is not known if xylometazoline is excreted in breast milk, therefore caution should be exercised and should be used only on the advice of a doctor whilst breastfeeding.
Storage:
Store in a cool and dry place. Protect from direct sunlight.