Mouthwash, also termed as oral rinse which is a liquid product used to rinse teeth, gums, and mouth. It contains an antiseptic to kill harmful bacteria present between your teeth and tongue. It contains Chlorhexidine Gluconate which is a disinfectant and topical anti-infective agent to prevent oral plaque. It is antimicrobial and bactericidal.
Therapeutic Indication:
● Treatment & prevention of gingivitis
● Maintenance of oral hygiene
Mechanism of Action:
Chlorhexidine is a broad-spectrum biocide effective against gram-positive bacteria, gram-negative bacteria and fungi. Chlorhexidine inactivates microorganisms and has a quicker kill rate than other antimicrobials. It shows bacteriostatic (inhibits bacterial growth) as well as bactericidal (kills bacteria) mechanisms of action, depending on its concentration. Chlorhexidine kills by disrupting the cell membrane is shown to have the unique ability to bind to the proteins present in human tissues such as skin and mucous membranes with limited systemic or bodily absorption. It is then released slowly over time to kill bacteria and fungi. This helps to reduce the bacterial count and prevents dental plaque. It has become a significant part of dentistry due to its ability to adhere to soft and hard tissue and maintain a potent sustained release.
Drug Interactions:
There is a potential for interaction with disulfiram when the product is swallowed.
Side Effects:
The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however Tongue discoloration, Mucosal irritation, Reversible brown staining of the teeth, Tooth staining and Decreased taste sensation can be observed in some patients.
Contraindications:
● Breast-feeding
● Dental work
● Infection, periodontal disease
● Ocular exposure
● Tympanic membrane perforation
● Children, infants, neonates
● Risk of serious hypersensitivity
●reactions or anaphylaxis
● Tobacco smoking
Precautions:
● Do not swallow the mouthwash
● Do not rinse your mouth with water or other mouthwashes right after using chlorhexidine gluconate
Storage:
Protect from light and store below 25°C.