This is the combination of omega-3-fatty acids, L – Methylfolate, Methylcobalamin with Pyridoxal – 5 Phosphate that are the daily supplements, especially for women in pregnancy and lactating period. These nutrients especially for fetal development and essential for its role in DNA; also helps to reduce or eliminate oxidative stress and lower homocysteine levels.
The composition is beneficial for the healthy development of the nerve cells, for depression, unstable mental behavior. It also improves the immunity system and helps to rebuild, restore, repair and maintains healthy cells. This is also used for low folate levels due to poor diet in pregnancy, renal dialysis and liver disorder.
Pregnancy is associated with physiologic changes that result in increased plasma volume and red blood cells and decreased concentrations of circulating nutrient-binding proteins and micronutrients. In many developing countries, these physiologic changes can be aggravated by under nutrition, leading to micronutrient deficiency states, such as anemia, that can have disastrous consequences for both mothers and newborn infants. The demand for both energy and nutrients is increased during pregnancy. For well-nourished women, only a small amount of additional energy is required because the body adapts to the increased energy requirements and becomes more energy efficient through reduced physical activity and a lowered metabolic rate.
The development of baby in the womb is accompanied by extensive changes in the body and there is a considerable increase in the nutritional needs of the mother. There are certain nutrients that play a vital role in pregnancy and you must be particular about their intake. It is important to take vitamin supplements when you are pregnant. This is because all the nutrients required by your body and the growing baby may not be met from your diet alone.
Irrespective of your consuming healthy, balanced diet it is recommended that you take vitamin supplements before and after you conceive. This will ensure that you get all the necessary nutrients required to conceive and have a safe and healthy pregnancy.
In this combination L-Methylfolate (LMF) is primary active form of folic acid and with high bioavailability. LMF in prenatal supplement had significantly higher hemoglobin level at the end of the second trimester and at delivery and have a benefit of lower incidences of anemia. Methylfolate prevent birth defects and produces healthy red blood cells to prevent anemia.
Pyridoxal Phosphate is the active form of vitamin B₆is converted to pyridoxal-5-phosphate (coenzyme) in the body. As a coenzyme, vitamin B₆ assists in an amazing variety of tasks – the creation of heme, the iron - containing component of red blood cells; making the hormone serotonin (the "feel good" hormone); processing carbohydrate for energy; keeping the nervous system working smoothly, and supporting hundreds of other jobs.
In pregnancy, Vitamin B₆ helps the liver process high levels of estrogen and progesterone hormones more efficiently and balance sodium levels, leading to a reduction in symptoms such as water retention. In one study, supplemental vitamin B₆ helped reduce the breast tenderness, headaches and weight gain associated with water retention. Vitamin B₆ reduces the risk of heart attacks up to 70%, significantly reduces morning sickness in pregnancy, and helps prevent complications of diabetes (in addition to burning feet).
Methylcobalamin belong to the class of cobalamin derivatives which is essential for Prenatal & Postnatal support. It is also important for the healthy development of the nerve cells.

Omega 3 Fatty acids contains:
EPA supports the heart, immune system, and inflammatory response,
DHA supports the brain, eyes, and central nervous systemand essential for the proper development and functionality of the brain, eyes, and heart, throughout the lifecycle.
The ratio of Methylcobalamin, Pyridoxal-5-phosphate and L-Methylfolate helps in bringing down the plasma level of homocysteine; the major risk factor for Atherosclerosis.Thus this combination reduces the major risk factors for Atherosclerosis.
A healthy diet during pregnancy should contain the right balance and combination of nutrients. Right nutrients are important; your baby's growth and development are dependent on your diet. A compromising diet during pregnancy can lead to weight gain, multiple nutritional deficiencies and pregnancy complications in mothers, which babies could be born with weight and congenital malformations.
So these nutrients in pregnant or breastfeeding are important for your baby's growth and development.

Indications & Usage:

• Prenatal & postnatal supplement
• Helps support fetal brain and eye development
• Prevention of neural tube defect
• Prophylaxis of hyperhomocysteinemia
• For the reduction of early preterm and very-low birth weight
• Promote restoration of lost cutaneous sensation in DPN (Diabetic Peripheral Neuropathy)
• Reduce oxidative stress & promote nerve health
• Creates healthy blood cells
• Improves nerve conduction velocity
• Supports the cardiovascular system
• Supports cell membranes

About Composition:

Omega-3-Fatty Acid:
Omega-3-fatty acids are essential fatty acids that must be consumed in the diet. Adequate consumption of omega-3-fatty acids is vitally important during pregnancy as they are critical building blocks of fetal brain and retina. Omega-3-fatty acids may also play a role in determining the length of gestation and in preventing perinatal depression. The most biologically active forms of omega-3-fatty acids are docosahexaenoic acid and eicosapentaenoic acid – both the development of a healthy baby and in the health of the mother.
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are two converted types of omega-3 essential fats and both arenaturally occur together and work together in the body; EPA supports the heart, immune system, and inflammatory response. DHA supports the brain, eyes, and central nervous system, which is why it is uniquely important for pregnant and lactating women.
Benefits of DHA & EPA:

• DHA may help in the pre- and post-natal health of both mother and child, particularly in the latter's brain development and overall immunity. EPA on the other hand, may help to modulate behavior and mood
• EPA and DHA are the dynamic duo of bio-available omega 3s. EPA and DHA may have increased benefits when consumed together. These include:
  • may help to slow the progression of age-related memory loss
  • may support memory and learning ability including focus and attention
  • may support healthy brain function and promote a positive mood and well-being
  • may help to maintain healthy triglyceride levels, while promoting the metabolism of dietary fat and cholesterol

L – Methylfolate:
L-Methylfolate is a substantially diastereoisomerically pure source of L-methylfolate containing not more than 1% D – form and it is the primary biologically active isomer of folic acid and the primary form of folate in circulation. L-methylfolate crosses the blood-brain barrier for use in the CNS. It exerts its action by enhancing synthesis of monoamine neurotransmitters, and has been categorized as a "trimonoamine modulator" because it is necessary for serotonin, dopamine, and norepinephrine synthesis. It is a good form which is all well absorbed.
Deficiencies of dietary folic acid can lead to abnormalities in the mother (anemia, peripheral neuropathy) and the fetus (congenital abnormalities). Dietary supplementation with folic acid around the time of conception has been known to reduce the risk of neural tube defects (NTDs). Folic acid is also thought to reduce the risk of preterm birth and congenital heart disease.It is always better to take the bioavailable form of any nutrient which guarantees that adequate amountsare being provided. About 40% to 60% of the population has genetic polymorphisms that impair theconversion of supplemental folic acid to its active form, L-methylfolate.

Pyridoxal-5-Phosphate:
Pyridoxal-5- phosphate is the active form of Vitamin B₆. Vitamin B₆ is found in one of three forms: pyridoxine hydrochloride, pyridoxal, or pyridoxamine. Inside the body, these forms of B₆ have to be converted by the liver to the active form the body needs - P5P. It is involved in many areas of your metabolism, from the formation of hemoglobin that carries oxygen in your blood, to the working of your genes, to the release of stored-up glucose in your muscles, and many other important actions including the formation of the biologic chemicals that nerves use to "talk to one another." And like vitamin B₁₂ it is also involved in the formation of the covering for nerves - the myelin sheath, this is one way in which it is directly supports nerve health.
Pyridoxine (Vitamin B₆) is used to treat nausea and vomiting in early pregnancy.Pyridoxine Phosphate (PLP) converts levodopa into dopamine. PLP then facilitates the conversion of the excitatory neurotransmitter glutamate to the inhibitory neurotransmitter GABA, and allows SAM to be decarboxylated to form propylamine, which is a precursor to polyamines.
P5P is the only form of B₆ that the fetus and newborn baby can use. In premature babies, who are more susceptible than full-term babies to SIDS, the use of the pyridoxine form of B₆ can result in irreversible central nervous system damage. And lack of P5P can predispose a surviving premature infant to atherosclerosis in later life. In addition, the fact that B₆ benefits some persons with Carpal Tunnel Syndrome, and not others, we think may well be traced to the person's ability or inability to make P5P from pyridoxine.
It's the P5P our bodies really need to break down and use fats, proteins, and carbohydrates, to make red blood cells and antibodies, to help the digestive and nervous systems function, and to maintain healthy skin.

Methylcobalamin:
Methylcobalamin, which is the active form of vitamin B₁₂, is used to support brain health, energy and healthy homocysteine levels. It is commonly used to prevent signs of a Vitamin B₁₂ deficiency. Methylcobalamin creates two major effects in the brain which are responsible for many of its neuro-protective, longevity enhancing benefits.
First, the compound eliminates excessive levels of homocysteine in the brain. This substance is often cited as the leading cause of vascular degeneration in the brain.
Next, Methylcobalamin improves the health and function of nerves in the brain. It can rebuild damaged nerves and contributes to the maintenance of function that is normally decayed during the aging process. It helps the nerve cells to function properly and even helps the damaged nerve cells to recover. It helps in the conversion of proteins and fats into energy. It is involved in the production of hemoglobin. It helps in the reduction of the level of homocysteine. It also contributes in the development and production of red blood cells.
Mecobalaminis helpful in the cases of both pre-natal and post-natal weakness, along with in neurological malfunctions and prevent neural tube defects.

Side Effects:
The product is possibly safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage.
However, some are: Appetite loss, stomach bloating, GI troubles, headache, nausea, vomiting, constipation, and sleepiness.

Special Precautions & Warnings: (For Pregnancy and Breast – Feeding mothers):
This supplement is especially for Pregnant and lactating mothers but it is to be noted that they should not take any single supplement in higher – than – normal doses unless recommended by a health – care provider for special conditions.

Storage:
Store in a cool, dry & dark place. Protected from direct sunlight.